Results 71 to 80 of about 21,276,578 (296)
Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]
, 2012 C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Lech, Maciej +12 more
core +1 more source
Advanced Science, EarlyView.An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li +7 more
wiley +1 more source
, 2019 Figure S2. Knockdown or overexpression of Galectin-1 in U251 or U87-MG cells. A. Galectin-1 was knocked down in U251 cell lines by SiRNA1â3. Galectin-1 siRNA2 and siRNA3 significantly reduced Galectin-1expression. B.
Shi Ma (217876) +12 more
core +1 more source
Advanced Science, EarlyView.Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao +19 more
wiley +1 more source
Advanced Science, EarlyView.Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan +11 more
wiley +1 more source
Galectin-1 Ameliorates Influenza A H1N1pdm09 Virus-Induced Acute Lung Injury
Frontiers in Microbiology, 2020 Influenza remains one of the major epidemic diseases worldwide. Acute lung injury mainly caused by excessive pro-inflammatory host immune responses leads to high mortality rates in severe influenza patients.
Jiaqi Bao +22 more
doaj +1 more source
Reduced expression of galectin-1 and galectin-9 by leucocytes in asthma patients
, 2012 Supported in part by EU–Mexico FONCICYT-C002-2009-1 ALA/127249, SAF-2008–02635 and SAF-2011–25834 from the Spanish Ministry of Science and Innovation, INDISNET (Redes Moleculares y Celulares en Enfermedades Inflamatorias) S2011/BMD-2332, MEICA (Molecular
Fuente, Hortensia de la +8 more
core +1 more source
Advanced Science, EarlyView.Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An +8 more
wiley +1 more source
Pathogens, 2020 HIV-1 CRF07_BC is a B’ and C subtype recombinant emerging virus and many of its viral characteristics remain unclear. Galectin-3 (Gal3) is a β-galactose binding lectin that has been reported as a pattern recognition receptor (PRR) and is known to mediate
Chih-Yen Lin +10 more
doaj +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda +4 more
wiley +1 more source