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101P Galectin 3 binding protein signature as early detection biomarker of glioma
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Galectin-3 Is a Nuclear Matrix Protein Which Binds RNA
Biochemical and Biophysical Research Communications, 1995The endogenous galectin-3 is a carbohydrate-binding protein of M(r) approximately 30,000 serving in the cytoplasm and on the cell surface as a receptor for ligands containing poly-N-acetyllactosamine sequences. In addition, galectin-3 has been demonstrated to be associated in the nucleus with ribonucleoprotein complexes and to act as a pre-mRNA ...
L, Wang, H, Inohara, K J, Pienta, A, Raz
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Revealing the Identity of Human Galectin-3 as a Glycosaminoglycan-Binding Protein
2022Human galectin-3 (Gal-3) is a β-galactoside-binding lectin. This multitasking protein preferentially interacts with N-acetyllactosamine moieties on glycoconjugates. Specific hydroxyl groups (4-OH, 6-OH of galactose, and 3-OH of glucose/N-acetylglucosamine) of lactose/LacNAc are essential for their binding to Gal-3.
Jared L, Edwards +3 more
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Carbohydrate binding proteins galectin-1 and galectin-3 in human trabecular meshwork
Experimental Eye Research, 2003Galectins are a family of carbohydrate binding proteins involved in a variety of biological processes including cell-cell and cell-matrix interactions. We examined galectin-1 and galectin-3 to determine if galectins are expressed in the human trabecular meshwork and Schlemm's canal.Human trabecular meshworks were dissected from donor eyes within 12 hr ...
Michael P, Fautsch +2 more
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Galectin-3 Binding Protein Contaminates the Purification of Recombinant Factor IX.
Blood, 2006Abstract The hemophilas are the most common severe hereditary bleeding disorders. The standard treatment of these disorders is to infuse plasma concentrates of the missing coagulation factor. However, the high cost of replacement therapy and the serious morbidity from the transmission of infectious agents have mandated a need for ...
Jacques Galipeau +2 more
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