Results 201 to 210 of about 43,794 (228)

Galectin 3‐binding protein is a potential contaminant of recombinantly produced factor IX

Haemophilia, 2007
Summary.  Haemophilia B, or factor IX (FIX) deficiency, represents 15% of the hereditary haemophilias. The serious morbidity from the transmission of infectious agents in plasma‐derived material has mandated a need for the production of recombinant product.
M, Blostein, J, Cuerquis, J, Galipeau
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Abstract 27: Galectin-3 Binding Protein: A New Factor Promoting Venous Thrombosis

Arteriosclerosis, Thrombosis, and Vascular Biology, 2012
Galectin-3 binding protein (Gal-3BP) was detected in procoagulant microparticles from mice and patients with venous thrombosis (VT), in prior studies from our laboratory. However, the mechanistic role of Gal-3BP and Galactin-3 (Gal-3) in the pathophysiology of thrombosis is unknown.
Jose A Diaz, Angela E Hawley, Shirley K Wrobleski, Evelyn Shea, Daniel D Myers, Thomas W Wakefield   +5 more
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Towards high affinity carbohydrate-binding proteins: Directed evolution of murine galectin-3

Canadian Journal of Chemistry, 2002
Towards a better understanding of the molecular basis of affinity, a directed evolution of murine galectin-3 (G3) was initiated to produce mutants with improved affinity for lactose and N-acetyllactosamine relative to the wild-type protein. A series of N-terminal truncations were developed to facilitate incorporation of the 35 kDa protein into a phage-
Joseph J Lundquist, Brendan M Kiburz, Jeffrey K Wu, Kenneth D Gibbs Jr., Eric J Toone   +4 more
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Plasma galectin-3-binding protein level in patients with systemic lupus erythematosus

Tanta Medical Journal, 2018
Background Systemic lupus erythematosus (SLE) is an autoimmune disorder that affects multiple organs. It is characterized by production of autoantibodies and immune complex deposition in various organs, leading to inflammation and tissue destruction. Although the definite etiopathogenesis of SLE remains unclear, many different mechanisms may contribute
SamahElsayed Abo-Elyazeed, ShereenF Gheida, GhadaAbdelMoamen Soliman, MohamedM Gamea   +3 more
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Serum galectin-3 and galectin-3 binding protein levels in Behçet's disease and their association with disease activity.

Clinical and experimental rheumatology, 2008
To determine the serum levels of galectin-3 (Gal-3) and galectin-3 binding protein (G3BP) and to evaluate the associations between clinical features and these levels in patients with Behçet's disease (BD).Fifty patients with BD (mean age 40.6 +/- SEM 1.4 years; 21 males, 29 females; 26 active and 24 inactive patients), 20 patients with rheumatoid ...
Y J, Lee, S W, Kang, J K, Song, J J, Park, Y D, Bae, E Y, Lee, E B, Lee, Y W, Song   +7 more
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Serum retinol binding protein 4 and galectin-3 binding protein as novel markers for postmenopausal nonalcoholic fatty liver disease

Clinical Biochemistry, 2018
To investigate the differential protein expression before and after menopause in women with nonalcoholic fatty liver disease (NAFLD) and to explore novel markers for menopausal NAFLD.Eight serum samples collected from pre- or post-menopausal women with NAFLD were analysed by iTRAQ 2D-LC-MS/MS. Two protein candidates were selected and verified by enzyme-
Hong, Cai, Sha, Lu, Yueming, Chen, Sayantana, Das Mbbs Mrcog, Zheng, Niu, Guangchao, Zhuo, Lei, Lai, Zhifen, Zhang   +7 more
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[Cancer-associated carbohydrate-binding protein galectin-3 and its therapeutic ligands].

Sheng li ke xue jin zhan [Progress in physiology], 2012
Carbohydrates are proved to be involved in recognition processes, including adhesion between cells, adhesion of cells to the extracellular matrix, and specific recognition of cells by one another. Galectin-3 is a nonenzymatic carbohydrate-binding protein present in mammals, whose conserved carbohydrate-recognition domain preferentially binds to ...
Hui, Bai, Li, Liu, Yu-Hua, Li, Yu, You, Qi-Bing, Mei   +4 more
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Galectin-3 Binding Protein and Galectin-3: Novel Factors Promoting Venous Thrombosis

Journal of Vascular Surgery: Venous and Lymphatic Disorders, 2013
J A, Diaz, A E, Hawley, S K, Wrobleski, E, Shea, E, DeRoo, R, Al-Khalil, D D, Myers, T W, Wakefield   +7 more
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Identifying potential inhibitors against galectin-3-binding protein (LGALS3BP) for therapeutic targeting of glioma

Journal of Biomolecular Structure and Dynamics
Glioblastoma is one of the most lethal types of Gliomas, and its treatment greatly depends on the stage of its detection. Galactin-3-binding protein (LGALS3BP) serves as a novel circulatory biomarker for detecting glioma at an early stage. This protein is also responsible for metastasis, proliferative signaling, angiogenesis, and immune system evasion ...
Kirti, Chauhan, Viswanathan, Vijayan, Pradeep, Pant, Sujata, Sharma, Md Imtaiyaz, Hassan, Nirmal Kumar, Ganguly, Pradeep, Sharma, Rashmi, Rana   +7 more
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Targeting galectin-driven regulatory circuits in cancer and fibrosis

Nature Reviews Drug Discovery, 2023
Karina V Mariño, Alejandro J Cagnoni, Gabriel A Rabinovich   +2 more
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