The role of galectins in modulating the tumor microenvironment and driving metastasis in skin cancers. [PDF]
Dabagh M +7 more
europepmc +1 more source
ABSTRACT Sputum culture conversion (SCC) at 2 months is an early indicator of tuberculosis (TB) treatment response, yet the associated immune alterations remain incompletely defined. We performed single‐cell RNA sequencing on peripheral blood mononuclear cells from eight TB patients, stratified by 2‐month SCC status.
Yiqun Xiong +9 more
wiley +1 more source
From Glycocode to Precision Oncology: Therapeutic Strategies Targeting Aberrant O-GalNAc Glycosylation in Cancer. [PDF]
Aasted MKM +5 more
europepmc +1 more source
ABSTRACT The peripheral nervous system (PNS) is responsible for innervating all regions of the body outside of the central nervous system (CNS), the latter consisting of the brain, spinal cord, and optic nerves. While myelin is an essential component for the efficient functioning of both CNS and peripheral nerve cells, it is particularly important for ...
Kathleen Margaret Hagen +1 more
wiley +1 more source
A glycosaminoglycan microarray identifies galectin-4 binding to sulfated glycosaminoglycans. [PDF]
Sano K +8 more
europepmc +1 more source
ABSTRACT Background and Aims To understand the experience of fatigue and cognitive impairment in adults with symptomatic primary sclerosing cholangitis (PSC) as an essential first step towards developing PSC‐specific symptom measures. Methods Purposeful sampling was used to identify 17 symptomatic adults from the PSC Symptom Assessment Project who met ...
Donna M. Evon +11 more
wiley +1 more source
Exploratory identification of candidate biomarkers and molecular contributors to paclitaxel-induced peripheral neuropathy in patients with breast cancer through proteomic analysis. [PDF]
Kittaka N +7 more
europepmc +1 more source
ABSTRACT Background and Aims Subclassifications of steatotic liver disease (SLD) are intended to provide a clinically meaningful framework for management. However, steatosis, cardiometabolic comorbidities and alcohol consumption are known to change over time.
Carmela Rapino +7 more
wiley +1 more source
Serum Apelin-13 and Galectin-3 in COVID-19: Associations With Routine Biochemical Parameters and Diagnostic Performance in a Case-Control Study. [PDF]
Uğurlu İ.
europepmc +1 more source
Functional Specialization of Clathrin‐Independent Endocytic Routes: Mechanisms and Cellular Roles
Distinct clathrin‐independent endocytic (CIE) routes support specialized cellular functions across different contexts. Created with Biorender.com. ABSTRACT Clathrin‐independent endocytosis (CIE) comprises a diverse repertoire of internalization mechanisms that operate in parallel with clathrin‐mediated endocytosis.
Andrea Francesco Benvenuto +5 more
wiley +1 more source

