Results 81 to 90 of about 9,659 (276)
Regulation of Eosinophil Recruitment and Activation by Galectins in Allergic Asthma
Frontiers in Medicine, 2017 Eosinophils are differentiated granulocytes that are recruited from the bone marrow to sites of inflammation via the vascular system. Allergic asthma is characterized by the presence of large numbers of eosinophils in the lungs and airways.
Savita P. Rao, Xiao Na Ge, P. Sriramarao
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BiomedicinesHead and Neck Squamous Cell Carcinoma (HNSCC) is a malignant cancer with a poor prognosis. Galectins (Gal) have been the subject of intensive research, but the comparative prognostic value of each Gal type is not yet understood.
Oriana Barros +4 more
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Galectins in tumor angiogenesis
, 2014 The expansion of solid tumors depends on the continuous ingrowth of new blood vessels out of pre-existing capillaries. Consequently, tumor neovascularization or tumor angiogenesis is considered a hallmark of cancer and an attractive target for cancer ...
Thijssen, V.L.J.L. +3 more
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Advanced high-affinity glycoconjugate ligands of galectins
, 2023 International audienceGalectins are proteins of the family of human lectins. By binding terminal galactose units of cell surface glycans, they moderate biological and pathological processes such as cell signaling, cell adhesion, apoptosis, fibrosis ...
Bumba, Ladislav +8 more
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Modulation of Animal Gut Health by Milk Oligosaccharide
Animal Research and One Health, EarlyView.This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen +7 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu +2 more
wiley +1 more source
, 2010 Galectins have been identified by proteomic profiling as abundantly produced excretory-secretory (ES) products of the lymphatic dwelling parasite, Brugia malayi.
Mongare, Margaret Mumbi
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Cell Communication and SignalingGalectins constitute a class of lectins that specifically interact with β-galactoside sugars in glycoconjugates and are implicated in diverse cellular processes, including transport, autophagy or signaling. Since most of the activity of galectins depends
Aleksandra Gędaj +9 more
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Neurobiology of DiseaseGalectins are β-galactoside-binding lectins that play increasingly mechanistic functions in central nervous system (CNS) physiology and disease. Over the past decade, a rapidly expanding literature has identified galectins as regulators of microglial ...
Jian Jing Siew, Yijuang Chern
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Galectins are widely distributed throughout the animal kingdom, from marine sponges to mammals. Galectins are a family of soluble lectins that specifically recognize β-galactoside-containing glycans and are categorized into three subgroups based on ...
Tomoko Tadokoro +8 more
core +1 more source