Results 151 to 160 of about 168,270 (320)

A Bioinformatic Approach Validated Utilizing Machine Learning Algorithms to Identify Relevant Biomarkers and Crucial Pathways in Gallbladder Cancer [PDF]

arXiv
Gallbladder cancer (GBC) is the most frequent cause of disease among biliary tract neoplasms. Identifying the molecular mechanisms and biomarkers linked to GBC progression has been a significant challenge in scientific research. Few recent studies have explored the roles of biomarkers in GBC.
arxiv  

Autochthonous Babesia canis infections in 49 dogs in Germany

Journal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 140-149, January/February 2023., 2023
Abstract Background Vector‐borne diseases are of increasing importance in Germany. Since 2015, autochthonous cases have been increasingly documented in Berlin/Brandenburg. Objectives Describe autochthonous Babesia canis infection in the Berlin/Brandenburg region. Animals Forty‐nine dogs with autochthonous B. canis infection.
Christiane Weingart, Christina S. Helm, Elisabeth Müller, Ingo Schäfer, Marianne Skrodzki, Georg von Samson‐Himmelstjerna, Jürgen Krücken, Barbara Kohn   +7 more
wiley   +1 more source

STUDIES ON GALLBLADDER FUNCTION. IX. THE ANION-CATION CONTENT OF BILE FROM THE NORMAL AND INFECTED GALLBLADDER [PDF]

, 1933
Charles G. Johnston, I. S. Ravdin, Cecilia Riegel, Clapp Allison   +3 more
openalex   +1 more source

Effect of cystic fibrosis modulator therapies on serum levels of fat‐soluble vitamins

JPGN Reports, EarlyView.
Abstract This is a prospective, multicenter study of a cohort of 224 cystic fibrosis (CF) patients treated with CF transmembrane conductance regulator (CFTR) modulators (CFTRm). Our aim was to prospectively analyze the effect of CFTRm treatment on fat‐soluble vitamin serum levels.
Elena Crehuá‐Gaudiza, Saioa Vicente Santamaría, Marina Álvarez Beltrán, Carmen Martín Fernández, Carlos Tutau Gómez, Inés Loverdos Eseverri, Ruth García Romero, Encarni Torcuato Rubio, Rodrigo Del Brío Castillo, María Garriga García, Celia Gascón Galindo, José Ramón Gutiérrez Martínez, Ana María Castro Millán, Sara Sierra San Nicolás, Pilar Ortiz Pérez, Camila García Volpe, Enrique Salcedo Lobato, Agustín De La Mano Hernández, Sara María Fernández González, Ana Reyes Domínguez, Luis Peña‐Quintana, David González Jiménez, Cystic Fibrosis and Pancreas Working Group of the Spanish Gastroenterology, Hepatology and Nutrition Paediatric Society (SEGHNP)   +23 more
wiley   +1 more source

Canine and feline P‐glycoprotein deficiency: What we know and where we need to go

Journal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 1-16, January 2023., 2023
Abstract In 2001 the molecular genetic basis of so‐called “ivermectin sensitivity” in herding breed dogs was determined to be a P‐glycoprotein deficiency caused by a genetic variant of the MDR1 (ABCB1) gene often called “the MDR1 mutation.” We have learned a great deal about P‐glycoprotein's role in drug disposition since that discovery, namely that P ...
Katrina L. Mealey, Jane G. Owens, Elaine Freeman   +2 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of Oncologic Liver Resections in Low‐ and Middle‐Income Countries: Opportunities to Improve Evidence and Outcomes

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Patients in low‐ and middle‐income countries (LMICs) are disproportionately affected by liver cancers but there is a lack of understanding of their postoperative outcomes. This study aimed to review the current status of research in LMICs regarding outcomes after oncologic hepatectomy and synthesize the data reported in the ...
Adel H. Khan, Omar Mahmud, Asad Saulat Fatimi, Shaheer Ahmed, Alyssa A. Wiener, Madhuri V. Nishtala, Christopher C. Stahl, Leslie Christensen, Muhammad Rizwan Khan, Patrick B. Schwartz, Syed Nabeel Zafar   +10 more
wiley   +1 more source

Development of extrahepatic bile ducts and mechanisms of tumorigenesis: Lessons from mouse models

Pathology International, Volume 72, Issue 12, Page 589-605, December 2022., 2022
Abstract The biliary system is a highly branched tubular network consisting of intrahepatic bile ducts (IHBDs) and extrahepatic bile ducts (EHBDs). IHBDs are derived from hepatic progenitor cells, while EHBDs originate directly from the endoderm through a separate branching morphogenetic process.
Hiroyuki Tomita, Akira Hara
wiley   +1 more source

LQ-Adapter: ViT-Adapter with Learnable Queries for Gallbladder Cancer Detection from Ultrasound Image [PDF]

arXiv
We focus on the problem of Gallbladder Cancer (GBC) detection from Ultrasound (US) images. The problem presents unique challenges to modern Deep Neural Network (DNN) techniques due to low image quality arising from noise, textures, and viewpoint variations.
arxiv  

Clinical problems caused by obesity [PDF]

, 2010
Over the past few decades the incidence of obesity has doubled worldwide and current estimates classify more than 1.5 billion adults as overweight and at least 500 million of them as clinically obese, with body mass index (BMI) over 25 kg/m2 and 30 kg ...
Kyrou, Ioannis, Weickert, Martin O.
core  

Genomic Profiling of Biliary Tract Cancers: Comprehensive Assessment of Anatomic and Geographic Heterogeneity, Co‐Alterations and Outcomes

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Biliary tract cancers (BTCs) represent distinct biological and genomic entities. Anatomic and geographic heterogeneity in genomic profiling of BTC subtypes, genomic co‐alterations, and their impact on long‐term outcomes are not well defined.
Diamantis I. Tsilimigras, Hunter Stecko, Dimitrios Moris, Timothy M. Pawlik   +3 more
wiley   +1 more source