Results 11 to 20 of about 194,069 (242)

IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization

open access: yesTranslational Oncology, 2023
Introduction: N6-methyladenosine (m6A) is an emerging epigenetic modification, which plays a crucial role in the development of cancer. Nevertheless, the underlying mechanism of m6A-associated proteins and m6A modification in gallbladder cancer remains ...
Jian Qin   +7 more
doaj   +1 more source

Gut microbiota promotes cholesterol gallstone formation by modulating bile acid composition and biliary cholesterol secretion

open access: yesNature Communications, 2022
Metabolic conditions associated with alterations of the gut microbiome, such as obesity and diabetes, predispose to gallstone disease. Here the authors demonstrate that the gut microbiome, in particular the genus Desulfovibrionale, contribute to ...
Hai Hu   +14 more
doaj   +1 more source

Laparoscopic or open liver resection for intrahepatic cholangiocarcinoma: A meta-analysis and systematic review

open access: yesFrontiers in Oncology, 2023
BackgroundAlthough laparoscopic hepatectomy has been widely used in the treatment of benign and malignant liver diseases, its applicability in intrahepatic cholangiocarcinoma (ICC) is controversial.
Xin Zhao   +16 more
doaj   +1 more source

Factors related to intestine have a role in prevention and treatment for gallstone disease [PDF]

open access: yesWaike lilun yu shijian, 2023
Gallstone is a common surgical disease. The factors which related to intestine during the process of gallstone formation have attracted increasing attention.
JIANG Zhaoyan, SHEN Weiyi, HU Hai
doaj   +1 more source

Effect of LncRNA GHET1 on Proliferation, Apoptosis, and Metastasis of Gallbladder Cancer Cells by Targeting miR-27b

open access: yesZhongliu Fangzhi Yanjiu, 2023
Objective To investigate the effect of GHET1 on the biological behavior of gallbladder cancer cells and the regulatory mechanism of GHET1 on miR-27b. Methods The expression of GHET1 and miR-27b in 50 samples of gallbladder cancer was detected by real ...
YANG Zhen, LI Wenchuan, ZHOU Ning
doaj   +1 more source

Relation of Gallbladder Motility to Viscosity and Composition of Gallbladder Bile in Patients with Cholesterol Gallstones [PDF]

open access: yes, 2009
Background/Aims: Increased viscosity and supersaturation of cholesterol in gallbladder bile, as well as an impaired motility of the gallbladder, are considered to be important factors in the pathogenesis of cholesterol gallstones.
Althaus, Rupert   +9 more
core   +1 more source

Peroxisomes in intestinal and gallbladder epithelial cells of the stickleback, Gasterosteus aculeatus L. (Teleostei) [PDF]

open access: yes, 1988
The occurrence of microbodies in the epithelial cells of the intestine and gallbladder of the stickleback, Gasterosteus aculeatus L., is described. In the intestine the organelles are predominantly located in the apical and perinuclear zone of the cells ...
AJH Ruiter de   +23 more
core   +4 more sources

The differentiation of cholesterol and pigment gallstones [PDF]

open access: yes, 1989
Gallbladder biles and stones were obtained at 116 cholecystectomies for symptomatic gallstone disease. All 33 patients younger than 50 years had cholesterol stones, whereas 40% of the older patients had pigment stones.
Carey   +5 more
core   +1 more source

The Value of Deep Learning in Gallbladder Lesion Characterization

open access: yesDiagnostics, 2023
Background: The similarity of gallbladder cancer and benign gallbladder lesions brings challenges to diagnosing gallbladder cancer (GBC). This study investigated whether a convolutional neural network (CNN) could adequately differentiate GBC from benign ...
Yunchao Yin   +5 more
doaj   +1 more source

NOViSE: a virtual natural orifice transluminal endoscopic surgery simulator [PDF]

open access: yes, 2016
Purpose: Natural Orifice Transluminal Endoscopic Surgery (NOTES) is a novel technique in minimally invasive surgery whereby a flexible endoscope is inserted via a natural orifice to gain access to the abdominal cavity, leaving no external scars.
Barrow, A   +4 more
core   +2 more sources

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