Results 11 to 20 of about 103,523 (321)

METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10

Cancer Cell International, 2022
Objective N6-methyladenosine (m6A) RNA methylation is involved in governing the mechanism of tumor progression. We aimed to excavate the biological role and mechanism of the m6A methyltransferase METTL3 in cholangiocarcinoma (CCA).
Jingli Cai, Zheng Cui, Jingyi Zhou, Bosen Zhang, Ruiqi Lu, Youcheng Ding, Hai Hu   +6 more
doaj   +1 more source

A-Kinase Anchor Protein 95 Is Involved in ERK1/2–Elk-1 Signal Transduction in Colon Cancer

Analytical Cellular Pathology, 2023
Objectives. To assess A-kinase anchor protein 95 (AKAP95), B-Raf, extracellular regulated protein kinases 1/2 (ERK1/2), and Elk-1 expression in colon cancer tissue, and characterize AKAP95 associations with B-Raf, ERK1/2, Elk-1, and colon cancer ...
Xiangyu Kong, Putian An, Junping Xu, Wenzhi Liu, Feng Lin, Yulong Yang   +5 more
doaj   +1 more source

Laparoscopic or open liver resection for intrahepatic cholangiocarcinoma: A meta-analysis and systematic review

Frontiers in Oncology, 2023
BackgroundAlthough laparoscopic hepatectomy has been widely used in the treatment of benign and malignant liver diseases, its applicability in intrahepatic cholangiocarcinoma (ICC) is controversial.
Xin Zhao, Xin Zhao, Feng-wei Gao, Feng-wei Gao, Feng-wei Gao, Kang-yi Jiang, Kang-yi Jiang, Jie Yang, Jie Yang, Qing-yun Xie, Qing-yun Xie, Jie Gong, Jie Gong, Man-yu Yang, Tian-yang Mao, Ze-hua Lei, Ze-hua Lei   +16 more
doaj   +1 more source

Gut microbiota promotes cholesterol gallstone formation by modulating bile acid composition and biliary cholesterol secretion

Nature Communications, 2022
Metabolic conditions associated with alterations of the gut microbiome, such as obesity and diabetes, predispose to gallstone disease. Here the authors demonstrate that the gut microbiome, in particular the genus Desulfovibrionale, contribute to ...
Hai Hu, Wentao Shao, Qian Liu, Ning Liu, Qihan Wang, Jin Xu, Xin Zhang, Zhenkun Weng, Qifan Lu, Long Jiao, Chaobo Chen, Haidong Sun, Zhaoyan Jiang, Xiaoping Zhang, Aihua Gu   +14 more
doaj   +1 more source

Tuberculosis of the Gallbladder [PDF]

HPB Surgery, 2000
Analysis of 5 patients with gallbladder tuberculosis who had open cholecystectomy and review of literature have shown that, although still rare it presents as a part of systemic miliary tuberculosis, abdominal tuberculosis, isolated gallbladder tuberculosis and as acalculus cholecystitis in anergic patients.
M. Ayub, Mohan Angala Kumar, H. S. Shukla, Kaja Srinivas Pavan Kumar, N. K. Keswani   +4 more
openaire   +3 more sources

Effect of LncRNA GHET1 on Proliferation, Apoptosis, and Metastasis of Gallbladder Cancer Cells by Targeting miR-27b

Zhongliu Fangzhi Yanjiu, 2023
Objective To investigate the effect of GHET1 on the biological behavior of gallbladder cancer cells and the regulatory mechanism of GHET1 on miR-27b. Methods The expression of GHET1 and miR-27b in 50 samples of gallbladder cancer was detected by real ...
YANG Zhen, LI Wenchuan, ZHOU Ning
doaj   +1 more source

LapSeg3D: Weakly Supervised Semantic Segmentation of Point Clouds Representing Laparoscopic Scenes [PDF]

, 2022
The semantic segmentation of surgical scenes is a prerequisite for task automation in robot assisted interventions. We propose LapSeg3D, a novel DNN-based approach for the voxel-wise annotation of point clouds representing surgical scenes. As the manual annotation of training data is highly time consuming, we introduce a semi-autonomous clustering ...
arxiv   +1 more source

Histoplasmosis of the gallbladder

IDCases, 2020
Histoplasmosis of the gallbladder is an extremely rare condition. We present the case of cholecystitis due to progressive, disseminated histoplasmosis in an immunocompetent woman.
Paul Saleeb, Cassidy W. Claassen, Christopher Grove   +2 more
openaire   +4 more sources

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

One-Shot Device Testing Data Analysis under Logistic-Exponential Lifetimes with an Application to SEER Gallbladder Cancer Data [PDF]

, 2022
In the literature, the reliability analysis of one-shot devices is found under accelerated life testing in the presence of various stress factors. The application of one-shot devices can be extended to the bio-medical field, where we often evidence that inflicted with a certain disease, survival time would be under different stress factors like ...
arxiv   +1 more source