Results 101 to 110 of about 55,687 (218)

Adjuvant Chemotherapy Regimens in Resected Biliary Tract Cancers: National, Comparative, Observational Study (TOG/GI‐SAFRADJU‐2501)

International Journal of Cancer, Volume 159, Issue 11, Page 2766-2777, 1 December 2026.
ABSTRACT The recommended adjuvant chemotherapy (adj‐ChT) regimen for resected biliary tract cancers (BTC) is capecitabine (Cape); yet, the recommendation is based on limited evidence. Although varied adj‐ChTs have been employed in practice, robust real‐world data is scarce. We conducted a national, multicenter, hospital‐based registry study to evaluate
Erman Akkus, Mehmet Kayaalp, Müzeyyen Aslı Ergözoğlu, Ilgın Koç Kuş, Doğan Bayram, Bilgeşah Kılıçtaş, Emel Ayvaz Güneyin, Ali Kalem, Haydar Temizyürek, Mehmet Mutlu Çatlı, Mehmet Sinan Akarca, Maral Martin Mıldanoğlu, Görkem Turhan, Mahmut Kara, Hacı Arak, Feyza Arslan Tan, Burak Paçacı, Berkay Yeşilyurt, Orhun Akdoğan, Emine Bihter Çetin, Selahattin Çelik, Fatma Keskin Uzundere, Elif Şahin, Zehra Sadak Öcal, Lamia Şeker Can, Bahadır Köylü, Mehmet Cem Fidan, Esmanur Kaplan Tüzün, Teoman Şakalar, Elif Sertesen Çamöz, Haydar Çağatay Yüksel, Onur Yazdan Balçık, Pınar Peker, Mehmet Yılmaz, Şeymanur Ala Enli, Erdem Kölemen, Sibel Oyucu Orhan, Yakup Düzköprü, Mustafa Ersoy, Tuğba Akın Telli, Mesut Yılmaz, Yusuf İlhan, Atila Yıldırım, Ramazan Coşar, Müslih Ürün, Arif Hakan Önder, Murat Araz, Ertuğrul Bayram, Havva Yeşil Çınkır, Ali Alkan, Mustafa Gürbüz, Nilüfer Avcı, Fatma Paksoy Türköz, İsmail Oğuz Kara, Fatih Köse, İlkay Tuğba Ünek, Ahmet Bilici, Öznur Bal, Şuayib Yalçın, Lorenza Rimassa, Hatime Arzu Yaşar   +60 more
wiley   +1 more source

New‐Onset Type 2 Diabetes Mellitus and Cancer Risk: A Matched Cohort Study in China Kadoorie Biobank

International Journal of Cancer, Volume 159, Issue 11, Page 2705-2719, 1 December 2026.
ABSTRACT The prevalence of type 2 diabetes mellitus (T2DM) is rising rapidly in China and is linked to increased cancer risk, but causality remains unclear due to biases. We examined the causal effect of T2DM on cancer risk using bias‐minimizing methods.
Mengying Wang, Owen Tipping, Bowen Liu, Derrick A. Bennett, Baiyong Shen, Siyi Zou, Shulin Zhao, Richard M. Martin, Matthew Sperrin, Andrew G. Renehan   +9 more
wiley   +1 more source

[Cancer of the gallbladder].

Harefuah, 1976
In the paper, the materials of clinical observation over 57 patients with the bladder cancer and the results of analysis of autopsy reports of 64 patients died from this lesion are presented. Cancer of the gallbladder affected mostly females (6 times as frequently as males) aged over 50 years.
M, Krispin, F C, Izsak
openaire   +3 more sources

Circular RNA circERBB2 Promotes Tumorigenesis via the miR‐1587/CBX2 Axis and Epigenetic Silencing of PTEN in Bladder Cancer Cells

MedComm – Oncology, Volume 5, Issue 4, December 2026.
circERBB2, originating from backsplicing of ERBB2 pre‑mRNA, is robustly upregulated in bladder cancer (BLCA) and acts as a miR‑1587 sponge to derepress chromobox 2 (CBX2). CBX2 subsequently recruits EZH2 to catalyze H3K27me3 deposition at the PTEN promoter, epigenetically silencing this tumor suppressor and unleashing the PI3K/AKT/mTOR cascade to drive
Xiang Pan, Xi Chen, Kailai Chen, Feng Pei, Li Zhong, Yunqi Li, Wenchao Shi, Jian Ma, Yakun Luo   +8 more
wiley   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3902-3913, November 2026.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

New therapeutic options for metabolic‐associated steatotic liver disease

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3770-3777, November 2026.
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley   +1 more source

Investigating Risk Factors for Delayed Melanoma Recurrence Beyond 5 Years Post‐Primary Tumor Diagnosis

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Patients undergoing treatment for cutaneous melanoma are generally considered cured after a period of 5 years, since most recurrences manifest within three to 5 years. However, some patients can present with a delayed recurrence of melanoma beyond a 10‐year timeframe.
Kaspar Itin, Rebecca Lapides, Soumya Paria, Babak Saravi, Alina. M. Torrez, Lara Valeska Maul, Michael Wang‐Evers, Alexander A. Navarini, Dieter Manstein, Beata Kun, Leticia Szadai, Judit Olàh, Eszter Baltas, Rolland Gyulai, Peter Hollo, Grzegorz Sarek, Istvan B. Németh, Kaustubh Adhikari, Elisabeth Roider   +18 more
wiley   +1 more source

A Rare Hepatoblastoma in a 10‐Year‐Old Boy Presenting With Tumor Rupture and Normal Alpha‐Fetoprotein Levels: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
A 10‐year‐old boy presented with a large hepatic mass (12.0 × 11.6 × 10.6 cm), classified as PRETEXT III, despite normal alpha‐fetoprotein levels (1.28 ng/mL). Tumor rupture necessitated emergency right trisectionectomy and radical colectomy. Histopathology confirmed mixed epithelial‐mesenchymal teratoid hepatoblastoma.
Christine Hyasint Paul, Andrew Swallow, Vulstan James Shedura, Albert Lazaro, Daniel Kitua, Ayubu Philipo, Daudi Katwana, Andrew K. Jackson, Georvin Haule, Cameron Gaskill, Kazungu Boniface Kahindi, Musa balowa, Godbless Massawe, Ally Mwanga   +13 more
wiley   +1 more source

The Efferocytosis‐Driven Macrophage Polarization: A Concerto in the Tumor Immunosuppressive Microenvironment

MedComm, Volume 7, Issue 11, November 2026.
Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen, Chunzhi Wu, Changquan Huang, Hang Zhou   +3 more
wiley   +1 more source

Protein Lactylation in Cancer: From Mechanisms to Therapy

MedComm, Volume 7, Issue 11, November 2026.
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang, Ping Hu, Shun Wang, Xide Zhang, Ziran Ye, Shengqiang Chen, Fu Gao, Yuanyuan Chen, Yanyong Yang   +8 more
wiley   +1 more source