Results 81 to 90 of about 53,197 (218)
intervention was wrong in 62% of their patients. In 50% of the patients, the initial diagnosis was a benign biliary disorder such as biliary colic (24%), acute colicystitis (12%), or choledocholithiasis (5%). In another 12% of patients, the gallbladder cancer was confused with a perihilar cholangiocarcinoma. As a result, 31% of the patients underwent a
openaire +4 more sources
Background The indications for extrahepatic bile duct (EHBD) resection remain a major controversy in the surgical management of patients with gallbladder cancer. On the other hand, perineural invasion (PNI) was reported as an important factor in patients
Suguru Maruyama +12 more
doaj +1 more source
Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney +10 more
wiley +1 more source
The emerging role of the Hippo signaling pathway in interorgan crosstalk
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song +2 more
wiley +1 more source
ABSTRACT Background Periodontitis is a prevalent chronic inflammatory condition that frequently co‐occurs with systemic chronic diseases. Although older adults experience a high burden of both periodontitis and chronic conditions, the extent to which age‐specific evidence has been synthesised remains unclear.
Manisha Tamrakar +4 more
wiley +1 more source
ABSTRACT Aim To evaluate the frequency, imaging characteristics, associated factors, and clinical significance of biliary abnormalities on imaging in patients receiving lenvatinib (LEN) plus cisplatin hepatic arterial infusion chemotherapy (HAIC) for hepatocellular carcinoma (HCC).
Hirohito Osanai +10 more
wiley +1 more source
Association of TREM1 expression with mTOR and DRP1 in gallbladder cancer: a study of 105 cases
Background Gallbladder cancer is highly aggressive and characterized by poor prognosis and limited treatment options. TREM1 (Triggering Receptor Expressed on Myeloid cells 1) may be involved in cancer inflammation and progression, but its relevance to ...
Ziyu Liu +6 more
doaj +1 more source
Abstract Objectives We aimed to determine the prevalence of metabolic disorders, liver steatosis and metabolic dysfunction‐associated steatotic liver disease (MASLD) in a cohort of middle‐aged women with HIV (WoWH) and to explore associations between liver steatosis, visceral fat depots and carotid atherosclerosis.
Mariacristina Poliseno +13 more
wiley +1 more source
ABSTRACT Background Associations between microbial dysbiosis and malignancies of the pancreatobiliary system have been described in recent studies. As a result of the limited number of studies that have been done specifically on the malignancies of the biliary tract, information regarding oral, biliary and tumour‐related microbial alterations was ...
Esperouz Fariba +5 more
wiley +1 more source
Codocytosis in the Dog: 345 Cases (2020–2022)
ABSTRACT Introduction Codocytes, or target cells, are a morphologic variation of erythrocytes characterized by increased membrane surface area relative to volume. In dogs, codocytosis is frequently noted on blood smear evaluation, but its clinical significance remains poorly understood. Objectives To characterize the clinical conditions associated with
Sarena M. Krojanker +5 more
wiley +1 more source

