Results 61 to 70 of about 53,197 (218)

Identification and Discrimination of Sulfated and Unsulfated Gut‐Hormone Biomarkers in Human Serum by Nanopore

Small, EarlyView.
This study discriminates between sulfated and unsulfated cholecystokinin‐8 gut‐hormone forms at single‐molecule‐level resolution. Using an aerolysin nanopore embedded in a hybrid lipid‐polymer membrane, the system produces distinct electrical signatures enabling highly sensitive detection, even in 20% human serum.
Luca Iesu, Laurent Bacri, Juan Pelta, Benjamin Cressiot   +3 more
wiley   +1 more source

Does Surgical Approach Influence Benchmark Attainment in Intrahepatic Cholangiocarcinoma?

World Journal of Surgery, EarlyView.
Intrahepatic cholangiocarcinoma (ICC) is a rare malignancy with rising incidence and poor prognosis. Surgical resection remains the only curative option, with outcomes driven by R0 margins and lymphadenectomy (LND). While open liver resection (OLR) is standard, laparoscopic (LLR) and robotic liver resection (RLR) are increasingly used, with concerns ...
Delphine Gastineau, Claire Goumard, Alexandre Doussot, Marc‐Antoine Allard, Raphael Venezia, Serena Langella, Guillaume Millet, Ruth Bustamante, Christian Hobeika, Rami Rhaiem, Stylianos Tzedakis, Heithem Jeddou, Bastien Le Floch, Alain Valverde, Nicolas Peru, Patrick Pessaux, Fabio Giannone, Jean Yves Mabrut, Kayvan Mohkam, Antonio Sa Cunha, Chady Salloum, Pierre Yves Blanc, Bertrand Le Roy, Takayuki Kawai, Olivier Farges, Stefan Hofmeyr, David Fuks, Stéphanie Truant, Daniel Cherqui, Alessandro Ferrero, Emmanuel Boleslawski, Jean‐Marc Regimbeau, Eric Vibert, Daniele Sommacale, Olivier Soubrane, Olivier Scatton, Alexis Laurent, Raffaele Brustia, on the behalf of the AFC‐ICC‐2009, AFC‐LLR‐2018, PRS‐2019 and FRIES‐ACHBPT‐2024 Study group   +40 more
wiley   +1 more source

Aspartate beta-hydroxylase is a prognostic factor in gallbladder cancer with the function of promoting tumorigenesis and chemoresistance

Frontiers in Endocrinology
AimsGallbladder cancer is characterized by a dismal prognosis, with a limited number of biological markers currently identified for the carcinogenesis, progression and prognosis of gallbladder cancers (GBCs).
Luo Yuan, Huang Yunpeng, Li Xiong, Yu Wen, Wang Yongxiang   +4 more
doaj   +1 more source

The Impact of Prehabilitation on Clinical Outcomes in Liver Surgery: A Systematic Review and Meta‐Analysis

World Journal of Surgery, EarlyView.
Major liver surgery is associated with significant physiological stress and a high rate of postoperative complications. Prehabilitation aims to enhance physiological reserve before surgery. Despite the growing volume of liver resections worldwide, the impact of prehabilitation on clinical and economic outcomes in patients undergoing elective liver ...
Lyrics M. Noba, Robyn J. Stiger, Declan F. J. Dunne, Lawrence D. Hayes, Christopher J. Gaffney, Ramani S. Moonesinghe, Ewen M. Harrison   +6 more
wiley   +1 more source

Comparison of thymidine phosphorylase expression and prognostic factors in gallbladder and bile duct cancer

BMC Cancer, 2010
Background Biliary tract cancers have limitations in information about different location-related pathogenesis and clinico-pathological characteristics.
You Young, Kim Dong-Goo, Chung Eun-Seon, Lee Myung, Won Hye, Hong Tae, Lee In-Seok   +6 more
doaj   +1 more source

Risk Factors for Cutaneous Immune‐Related Adverse Events in the Japanese Population: A Retrospective Single‐Center Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe, Kohei Yamakawa, Miyu Kobayashi, Yusuke Saigusa, Yukie Yamaguchi   +4 more
wiley   +1 more source

Women's and Health Care Professionals' Experiences of Discontinuing Hormone Replacement Therapy (HRT): A Systematic Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Hormone Replacement Therapy (HRT) is used to manage menopausal symptoms, particularly vasomotor symptoms (VMS). HRT prescribing rates are rising, but most women will eventually discontinue. Objectives To explore the experiences of women stopping HRT, why women restart HRT, and the HCPs advising them. Search Strategy Embase, MEDLINE,
Sarah Bunnewell, Sabrina Keating, Jo Parsons, Martha Hickey, Sarah Hillman   +4 more
wiley   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Dynamic SPECT Assessment of Hepatic Function in Patients With Liver Disease: A Systematic Review and Meta‐Analysis

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Dynamic Single Photon Emission Computed Tomography (dynSPECT) is an advanced functional imaging modality that enables estimation of temporal changes in radiopharmaceutical distribution and physiological function. While dynSPECT has been employed in several clinical applications, it has not been widely applied to liver imaging ...
Bader Aloufi, Roger Fulton, Kathy Willowson, Peter L. Kench   +3 more
wiley   +1 more source

Controversial points in the surgical treatment of gallbladder cancer with delayed diagnoses [PDF]

Waike lilun yu shijian
Gallbladder cancer with delayed diagnoses, as a malignant tumor diagnosed intraoperatively or postoperatively incidentally in benign gallbladder diseases, radical surgical treatment is its core treatment, and the necessity of re-operation, timing of ...
LE Sen, ZUO Yue, DENG Zhengdong, WANG Jianming
doaj   +1 more source