Results 121 to 130 of about 89,135 (337)

A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel. [PDF]

, 2019
Pexidartinib (PLX3397) is a small molecule tyrosine kinase and colony-stimulating factor-1 inhibitor with FDA breakthrough therapy designation for tenosynovial giant-cell tumor, and currently under study in several other tumor types, including breast ...
Chien, A Jo, Esserman, Laura J, Hyland, Colby, Piawah, Sorbarikor, Rugo, Hope S, Umetsu, Sarah E   +5 more
core  

lncDILC Downregulation in Liver Cancer‐Associated Fibroblasts Drives Pro‐Invasive Conversion via a miR‐6071‐ZNF395 Axis

Cancer Science, EarlyView.
We found in the present study the loss‐of‐function of a sequential inhibitory cascade of lncDILC‐miR‐6071‐ZNF395 in liver CAFs, which promoted the NF‐CAF conversion through increasing expression of pro‐invasive cytokines like IL‐6, LIF, CXCL12, and TGF‐β.
Yawen Li, Jilong Liu, Shentao Tai, Dandan Tong, Bifeng Wang, Dingbing Lu, Guoqing Shi, Xuemei Liu   +7 more
wiley   +1 more source

Primary Pure Squamous Cell Carcinoma of the Gallbladder Locally Invading the Liver, Duodenum, and Stomach: A Case Report and Literature Review

Case Reports in Surgery, 2017
Primary pure squamous cell carcinoma (SCC) of the gallbladder is an exceptionally rare type of tumor that comprises only 1% of all gallbladder cancer. SCC of the gallbladder portends a worse prognosis than the more common adenocarcinoma variant because ...
Aldrin C. Alpuerto, Maximo E. Mora, R. Jonathan Robitsek, Sebastian D. Schubl   +3 more
doaj   +1 more source

Synergistic associations of metformin and GLP‐1 receptor agonist use with adiposity‐related cancer incidence in people living with type 2 diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Background Metformin and glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) may reduce the risk of adiposity‐related cancers in patients with type 2 diabetes (T2D). The potential synergistic effects of these treatments on cancer incidence remain unclear, considering their distinct biological mechanisms and their associated effects on body ...
Alex E. Henney, Megan Heague, David R. Riley, Theresa J. Hydes, Matthew Anson, Uazman Alam, Daniel J. Cuthbertson   +6 more
wiley   +1 more source

Propofol induces proliferation and invasion of gallbladder cancer cells through activation of Nrf2 [PDF]

, 2012
Lingmin Zhang, Ning Wang, Suna Zhou, Wenguang Ye, Gui-xia Jing, Mingxin Zhang   +5 more
openalex   +1 more source

Gallbladder cancer-associated fibroblasts promote vasculogenic mimicry formation and tumor growth of gallbladder cancers via upregulating the expression of NOX4, a poor prognosis factor, through activating IL-6-JAK-STAT3 signal pathway [PDF]

, 2020
Mu‐Su Pan, Hui Wang, Kamar Hasan Ansari, Xinping Li, Wei Sun, Yue‐Zu Fan   +5 more
openalex   +1 more source

New‐onset prediabetes/diabetes worsens overall survival in patients with cancer: A real‐world retrospective cohort study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Cancer diagnosis may increase the risk of developing prediabetes/diabetes and subsequently worsen survival in cancer patients. However, it is unclear whether this association is influenced by the timing of hyperglycemia onset or the use of antihyperglycemic medications.
Maci Winn, Svenja Pauleck, Stephanie Richardson, Richard Viskochil, Prasoona Karra, Howard Colman, Jennifer A. Doherty, Yizhe Xu, Siwen Hu‐Lieskovan, Michelle Litchman, Mary C. Playdon, Sheetal Hardikar   +11 more
wiley   +1 more source

Global, regional, and national burden and trends analysis of gallbladder and biliary tract cancer from 1990 to 2019 and predictions to 2030: a systematic analysis for the Global Burden of Disease Study 2019

Frontiers in Medicine
ObjectivesOur aim was to explore the disease burden caused by gallbladder and biliary tract cancer globally, regionally, and nationally, by age and sex.MethodsThe absolute number of cases and age-standardized rates (ASR) of incidence, prevalence ...
Jiao Su, Yuanhao Liang, Xiaofeng He
doaj   +1 more source

Nomogram for Predicting the Benefit of Adjuvant Chemoradiotherapy for Resected Gallbladder Cancer [PDF]

, 2011
Samuel J. Wang, Andrew Lemieux, Jayashree Kalpathy–Cramer, Celine Bicquart Ord, Gary V. Walker, Clifton D. Fuller, Jong Sung Kim, Charles R. Thomas   +7 more
openalex   +1 more source

Laparoscopic Extended Cholecystectomy for Patients with Gallbladder Cancer [PDF]

, 2023
S. Curitol Sanchez, N. Portillo López, A. Troncoso Trujillo, H. Losada Morales, O. Arias Rovira, L. Acencio Barrientos   +5 more
openalex   +1 more source