Bile acid metabolism and signaling in human and animal health: A One Health perspective
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li +7 more
wiley +1 more source
Correction: The B7 family subgroup reflects tumor cell heterogeneity and patient post-operative prognosis in gallbladder cancer. [PDF]
Ma C +10 more
europepmc +1 more source
ABSTRACT Objective To investigate whether the neutrophil percentage‐to‐albumin ratio (NPAR) predicts 28‐ and 365‐day mortality in ICU patients with acute pancreatitis (AP) and improves the performance of existing ICU scoring systems. Methods We extracted data on 437 ICU AP patients from the MIMIC‐IV 3.0 database.
Chunyan Wang +3 more
wiley +1 more source
Perspectives and preferences on palliative chemotherapy-immunotherapy in gallbladder cancer patients. [PDF]
Dora KA +5 more
europepmc +1 more source
The Evolution of Medications for Obesity Management
ABSTRACT This narrative review provides an overview of progress in the development of obesity medications, including a synthesis of data describing the efficacy and safety of currently available agents and emerging therapeutic options. Historically, many obesity medications have been withdrawn from the market due to safety concerns.
Jaskirath Gill, Priya Sumithran
wiley +1 more source
OLFM4 orchestrates the immunosuppressive microenvironment and drives gallbladder cancer progression. [PDF]
Li W, Liu K, Yang F, He H, Wen W.
europepmc +1 more source
ABSTRACT Background The optimal protocol for clinical liver 31P‐magnetic resonance spectroscopy (MRS) remains unclear. Single‐voxel 31P‐MRS using image‐selected in vivo spectroscopy (ISIS) employs respiratory‐triggering (RT) or free‐breathing (FB) acquisition.
Kumi Ozaki +5 more
wiley +1 more source
Editorial Expression of Concern: Aprepitant inhibits the development and metastasis of gallbladder cancer via ROS and MAPK activation. [PDF]
Cao X +9 more
europepmc +1 more source
RNA‐Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities
RNA‐binding proteins (RBPs) regulate RNA stability, localization, translation, and splicing through intrinsic binding domains and interactions with diverse cellular partners. Their competitive and cooperative networks shape disease‐related RNA programs, especially in cancer.
Ling Li, Xiuli Yan, Qing Ji, Hui Zhang
wiley +1 more source
Synchronous Intra-ampullary Papillary-Tubular Neoplasm and Gallbladder Cancer. [PDF]
Suto K +11 more
europepmc +1 more source

