Results 201 to 210 of about 57,324 (279)

Intrahepatic Cholangiocarcinoma: Epidemiological Trends, Risk Factors, Diagnostic Challenges, and Advances in Personalized Therapy—A Comprehensive Review

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1701-1721, June 2026.
ABSTRACT Intrahepatic cholangiocarcinoma (iCCA) ranks as the second most common primary liver cancer, compared to about 20% of cases. Its global incidence has climbed over the past four decades, yet early detection remains indefinable due to its asymptomatic nature. Five‐year survival rate of approximately is under 10%.
Yaqoob Muhammad, YuZhu Jin, Kai Luo, He Bai, Xudong Zhang, Xu Sun, Zahoor Maheen, Ali Tanveer, Saeed Muddasar Muhammad, Jialin Qu, Guixin Zhang   +10 more
wiley   +1 more source

Occult Nodal Disease in Gallbladder Cancer: An International Multi-institutional Analysis and Preoperative Risk Stratification. [PDF]

Ann Surg Oncol
Kawashima J, Yuza K, Endo Y, Sahara K, Aucejo F, Marques HP, Hugh T, Kitago M, Ruzzenente A, Homma Y, Endo I, Pawlik TM.   +11 more
europepmc   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

Single-Centre Experience of Gallbladder Cancer in the United Kingdom: Do Patients With Incidentally Discovered Malignancy After Gallbladder Surgery Have Better Outcomes? [PDF]

Cureus
Eskandar G, Abuahmed M, Rashid R, Hammouda A, Wilson J, Magee C.   +5 more
europepmc   +1 more source

Metabolic Syndrome and Obesity‐related cancer Risk and Survival: An Umbrella Review of Systematic Reviews With Meta‐analysis of Observational Studies

Obesity Reviews, Volume 27, Issue 6, June 2026.
ABSTRACT Introduction Metabolic syndrome (MetS) may be associated with obesity‐related cancer (ORC) owing to shared risk factors like physical inactivity, insulin resistance, gut microbiome dysfunction, and inflammation. We conducted an umbrella review of systematic reviews with meta‐analysis to synthesize the evidence on the association between MetS ...
Maci Winn, Prasoona Karra, Ryzen Benson, Svenja Pauleck, Nathorn Chaiyakunapruk, Win Khaing, Sajesh K. Veettil, Mary M. McFarland, Tallie Casucci, Yizhe Xu, Siwen Hu‐Lieskovan, Michelle Litchman, Mary Playdon, Sheetal Hardikar   +13 more
wiley   +1 more source

Chronic Cholestatic Liver Disease Induced by Larval Ascariasis: Novel Insights Into Immune‐Mediated Pathogenesis and Hepatic Fibrosis in Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Liver alterations induced by single infection (SI) or reinfection (RE) with 250 or 2500 Ascaris suum eggs in mice. Histological analysis shows inflammatory cell infiltration (eosinophils, lymphocytes, macrophages, and neutrophils), fibrotic areas, and bile duct proliferation in infected animals compared with uninfected controls.
Jorge Lucas Nascimento Souza, Chiara Cássia Oliveira Amorim, Ana Rafaela Antunes‐Porto, Fernanda Rezende Souza, Evelyn Ane Oliveira, Izabela da Silva Oliveira, Isabela de Brito Duval, Andressa Mariana Saldanha‐Elias, Marcelo Eduardo Cardozo, Ramayana Morais de Medeiros Brito, Luisa Mourão Dias Magalhães, Geovanni Dantas Cassali, Neima Briggs, Ricardo Toshio Fujiwara, Remo Castro Russo, Guilherme Grossi Lopes Cançado, Lilian Lacerda Bueno   +16 more
wiley   +1 more source

Phosphoglucomutase 5 suppresses gallbladder cancer progression by inhibiting lactate-driven STAT3 signaling. [PDF]

Transl Oncol
Ma W, Zhang C, Gou A, Hu M, Huang Y, Jiang X, Ao J, Wang J.   +7 more
europepmc   +1 more source

Phosphinate or Urea? Synthesis and Biological Evaluation of Prostate Specific Membrane Antigen‐Targeted Fluorophores With Different Zinc‐Binding Motif

ChemMedChem, Volume 21, Issue 10, 27 May 2026.
A comparison of two structurally related prostate specific membrane antigen (PSMA)‐targeted fluorophores revealed that the substitution of the urea motif lysine‐urea‐glutamate (KuE) by a phosphinate leads to probes with low nanomolar PSMA‐affinity, good and specific tumor uptake, and low off‐target tissue retention in mice.
Lennart F. V. Spickschen, Svenja Kerpa, Tetiana Titko, Roland Thünauer, John M. Van Wazer, Amanda Fears, Amy Cao, Matthew D. Silva, Daniel L. J. Thorek, Elke Oetjen, Wolfgang Maison   +10 more
wiley   +1 more source

Revealing the Potential Associations of Mutation-Related Genes with Lymph Node Metastasis in Gallbladder Cancer Through Transcriptome and Exome Sequencing. [PDF]

Biomedicines
Li Q, Tang Q, Xue D, Liu H, Tang Z, Zhang D, Chen C, Geng Z.   +7 more
europepmc   +1 more source