Results 221 to 230 of about 89,135 (337)

Localized IgG4-related Cholecystitis Mimicking Gallbladder Cancer

open access: diamond, 2015
Tadahisa Inoue   +11 more
openalex   +1 more source

Safety, Tolerability, and Pharmacokinetics of a Novel Nitroimidazooxazole Antitubercular Agent in Healthy Adults: A Phase I Trial

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Mean blood drug concentration–time curves (linear and semi‐logarithmic) of JBD0131 in the (A) single‐dose group; (B) food‐affected group. ABSTRACT This study evaluated the safety, tolerability, and pharmacokinetics of JBD0131, a novel nitroimidazooxazole antitubercular agent, in healthy adults.
Jia Miao   +9 more
wiley   +1 more source

Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu   +5 more
wiley   +1 more source

Global, Regional, and National Burden of Cancer in the Elderly Population, 1990–2021: Analysis of Data From the Global Burden of Disease Study 2021

open access: yesMed Research, Volume 1, Issue 3, Page 440-454, December 2025.
ABSTRACT With the global aging trend intensifying, cancer presents a significant health challenge for the elderly. This study aims to assess the prevalence, mortality, and disability‐adjusted life years (DALY) burden of cancer among individuals aged 60–94 worldwide from 1990 to 2021.
Xiaohan Zhu   +4 more
wiley   +1 more source

Correction: Efficacy and safety of lenvatinib combined with anti-PD-1 antibodies plus GEMOX chemotherapy as non-first-line systemic therapy in advanced gallbladder cancer [PDF]

open access: gold
Yang Tan   +14 more
openalex   +1 more source

Application of the Da Vinci Single‐Port (SP) Robot in General Surgery: A First Systematic Review

open access: yesThe International Journal of Medical Robotics and Computer Assisted Surgery, Volume 21, Issue 6, December 2025.
ABSTRACT Introduction Minimally invasive surgery has revolutionized surgical practice by reducing surgical trauma and enhancing recovery. In this context, the da Vinci SP System represents a major technological advancement. This review aims to report its clinical applications in general surgery, evaluating associated outcomes and potential advantages ...
Antonio Cubisino   +2 more
wiley   +1 more source

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