Results 21 to 30 of about 89,135 (337)

Genetic mutational analysis of β-catenin gene affecting GSK-3β phosphorylation plays a role in gallbladder carcinogenesis: Results from a case control study

Cancer Treatment and Research Communications, 2020
This manuscript has reported different mutations of β-catenin gene in gallbladder cancer patients which affect GSK-3β phosphorylation site. Purpose: Gallbladder carcinoma (GBC) is a relatively rare and fatal cancer with poor prognosis.
Ruhi Dixit, Manoj Pandey, Sunil Kumar Tripathi, Amit Nandan Dhar Dwivedi, Vijay Kumar Shukla   +4 more
doaj   +1 more source

Radiation therapy for primary carcinoma of the extrahepatic biliary system. An analysis of 63 cases. [PDF]

, 1991
From 1976 to 1988, 63 patients received radiation therapy for primary cancers of the extrahepatic biliary system (eight gallbladder and 55 extrahepatic biliary duct). Twelve patients underwent orthotopic liver transplantation.
Carr, BI, Epstein, AH, Flickinger, JC, Iwatsuki, S, Starzl, TE   +4 more
core   +1 more source

MicroRNA-125b predicts clinical outcome and suppressed tumor proliferation and migration in human gallbladder cancer

Tumor Biology, 2017
We intended to investigate the functional role and clinical relevance of microRNA-125b in human gallbladder cancer. Quantitative real-time polymerase chain reaction was used to examine microRNA-125b expression in gallbladder cancer cell lines, and 79 ...
Liang Yang, Sheng Huang, Hongbin Ma, Xiaoxiong Wu, Feiling Feng   +4 more
doaj   +1 more source

Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy

Molecular Cancer, 2019
Background Gallbladder cancer is the most common biliary tract malignancy and not sensitive to chemotherapy. Autophagy is an important factor prolonging the survival of cancer cells under chemotherapeutic stress.
Qiang Cai, Shouhua Wang, Longyang Jin, Mingzhe Weng, Di Zhou, Jiandong Wang, Zhaohui Tang, Zhiwei Quan   +7 more
doaj   +1 more source

The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]

, 2019
Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A., D'arpa F., Di Carlo P., Fasciana T., Giammanco A., Gulotta G., Rodolico V., Sergi C., Serra N.   +8 more
core   +1 more source

A Multiorgan Trafficking Circuit Provides Purifying Selection of Listeria monocytogenes Virulence Genes. [PDF]

, 2019
Listeria monocytogenes can cause a life-threatening illness when the foodborne pathogen spreads beyond the intestinal tract to distant organs. Many aspects of the intestinal phase of L. monocytogenes pathogenesis remain unknown.
Becattini, Simone, Louie, Alexander, Portnoy, Daniel A, Waldor, Matthew K, Zhang, Ting   +4 more
core   +2 more sources

Acetylation stabilizes stathmin1 and promotes its activity contributing to gallbladder cancer metastasis

Cell Death Discovery, 2022
Gallbladder cancer is the most common biliary tract malignant tumor with highly metastatic characters and poor prognosis. However, the underlying mechanism remains unclear. Stathmin1 is ubiquitous phosphoprotein, regulating microtubule stabilization.
Kun Fan, Xiaojian Ni, Sheng Shen, Zijun Gong, Jiwen Wang, Yanlei Xin, Bohao Zheng, Wentao Sun, Han Liu, Tao Suo, Xiaoling Ni, Houbao Liu   +11 more
doaj   +1 more source

Dihydroartemisinin inhibits TCTP-dependent metastasis in gallbladder cancer

Journal of Experimental & Clinical Cancer Research, 2017
Background Patients with metastatic or relapsed gallbladder cancer generally have a poor prognosis. Therefore, targeting metastasis is one arm of therapeutic strategies to treat gallbladder cancer.
Fei Zhang, Qiang Ma, Zihang Xu, Haibin Liang, Huaifeng Li, Yuanyuan Ye, Shanshan Xiang, Yijian Zhang, Lin Jiang, Yunping Hu, Zheng Wang, Xuefeng Wang, Yong Zhang, Wei Gong, Yingbin Liu   +14 more
doaj   +1 more source

Gallbladder cancer: current and future treatment options

Frontiers in Pharmacology, 2023
Surgery remains the preferred treatment option for early-stage gallbladder cancer (GBC). According to the anatomical position of the primary tumor, accurate preoperative stage and strict control of surgical indications, appropriate surgical strategies ...
Yanzhao Zhou, Yanzhao Zhou, Kun Yuan, Yi Yang, Zemin Ji, Dezheng Zhou, Jingzhong Ouyang, Zhengzheng Wang, Fuqiang Wang, Chang Liu, Qingjun Li, Qi Zhang, Qiang Li, Xiao Shan, Jinxue Zhou   +14 more
doaj   +1 more source

Disease Burden of Gallbladder Cancer in China from 1990 to 2019 and the Analysis of Its Future Trends [PDF]

Zhongguo quanke yixue
Background Gallbladder cancer is featured by difficult early detection, poor treatment effectiveness and high mortality. An in-depth epidemiology research of gallbladder cancer can provide valuable data for the formulation of prevention and treatment ...
LIU Shanshan, LI Chuyi, ZHENG Ying, LU Lixia, LI Bin, YU Xiaohui, DANG Zheng
doaj   +1 more source