Results 21 to 30 of about 78,261 (320)
Gallbladder cancer: South American experience [PDF]
, 2016 Large differences in terms of incidence and mortality due to gallbladder cancer (GBC) have been reported worldwide. Moreover, it seems that GBC has unique characteristics in South America.
Arroyo, Gerardo F. +2 more
core +1 more source
Tumor Biology, 2017 We intended to investigate the functional role and clinical relevance of microRNA-125b in human gallbladder cancer. Quantitative real-time polymerase chain reaction was used to examine microRNA-125b expression in gallbladder cancer cell lines, and 79 ...
Liang Yang +4 more
doaj +1 more source
Molecular Cancer, 2019 Background Gallbladder cancer is the most common biliary tract malignancy and not sensitive to chemotherapy. Autophagy is an important factor prolonging the survival of cancer cells under chemotherapeutic stress.
Qiang Cai +7 more
doaj +1 more source
Targeted therapy of advanced gallbladder cancer and cholangiocarcinoma with aggressive biology: eliciting early response signals from phase 1 trials. [PDF]
, 2013 PurposePatients with advanced cholangiocarcinoma (CC) and gallbladder carcinoma (GC) have few therapeutic options for relapsed disease. methods: Given the overall poor prognosis in this population and the availability of novel targeted therapies, we ...
Falchook, Gerald S +14 more
core +2 more sources
, 2023 Gallbladder carcinoma is a form of cancer that develops in the gallbladder, an organ located beneath the liver. This condition poses a clinical challenge due to its late diagnosis and aggressive tumor behavior. Risk factors include the presence of gallstones, advanced age, and obesity.
de Werra, Carlo +8 more
openaire +2 more sources
Topoisomerase expression and amplification in solid tumours: Analysis of 24,262 patients. [PDF]
, 2017 BackgroundTopoisomerase I (TOPO1) and topoisomerase IIα (TOP2A) are specific targets of multiple chemotherapy drugs. Increased expression of TOPO1 protein and amplification of the TOP2A gene have been associated with treatment response in colorectal and ...
Arguello, David +4 more
core +1 more source
Association of diverse bacterial communities in human bile samples with biliary tract disorders: a survey using culture and polymerase chain reaction-denaturing gradient gel electrophoresis methods [PDF]
, 2016 Bacterial infection is considered a predisposing factor for disorders of the biliary tract. This study aimed to determine the diversity of bacterial communities in bile samples and their involvement in the occurrence of biliary tract diseases. A total of
Alebouyeh, M. +5 more
core +1 more source
Cell Death Discovery, 2022 Gallbladder cancer is the most common biliary tract malignant tumor with highly metastatic characters and poor prognosis. However, the underlying mechanism remains unclear. Stathmin1 is ubiquitous phosphoprotein, regulating microtubule stabilization.
Kun Fan +11 more
doaj +1 more source
Mirizzi syndrome associated with hepatic artery pseudoaneurysm: a case report. [PDF]
, 2008 INTRODUCTION: This is the first case report of Mirizzi syndrome associated with hepatic artery pseudoaneurysm. CASE PRESENTATION: A 54-year-old man presented with painful obstructive jaundice and weight loss.
Brian R. Davidson +11 more
core +3 more sources
Gallbladder cancer: current and future treatment options
Frontiers in Pharmacology, 2023 Surgery remains the preferred treatment option for early-stage gallbladder cancer (GBC). According to the anatomical position of the primary tumor, accurate preoperative stage and strict control of surgical indications, appropriate surgical strategies ...
Yanzhao Zhou +14 more
doaj +1 more source