Results 21 to 30 of about 90,478 (344)

MBD1 promotes the malignant behavior of gallbladder cancer cells and induces chemotherapeutic resistance to gemcitabine

Cancer Cell International, 2019
Background Methyl-CpG binding domain protein 1 (MBD1), which couples DNA methylation to transcriptional repression, has been implicated in transcriptional regulation, heterochromatin formation, genomic stability, cell cycle progression and development ...
Liu Wensheng, Zhang Bo, Hu Qiangsheng, Xu Wenyan, Ji Shunrong, Xu Jin, Ni Quanxing, Yu Xianjun, Xu Xiaowu   +8 more
doaj   +1 more source

Genetic mutational analysis of β-catenin gene affecting GSK-3β phosphorylation plays a role in gallbladder carcinogenesis: Results from a case control study

Cancer Treatment and Research Communications, 2020
This manuscript has reported different mutations of β-catenin gene in gallbladder cancer patients which affect GSK-3β phosphorylation site. Purpose: Gallbladder carcinoma (GBC) is a relatively rare and fatal cancer with poor prognosis.
Ruhi Dixit, Manoj Pandey, Sunil Kumar Tripathi, Amit Nandan Dhar Dwivedi, Vijay Kumar Shukla   +4 more
doaj   +1 more source

Updated management of malignant biliary tract tumors: an illustrative review [PDF]

, 2016
The management of malignant biliary tumors (MBTs) is complex and requires a multidisciplinary approach. Guidelines and methods of staging for biliary tumors have recently been released by main international societies, altering the clinical and radiologic
Cannavale, Alessandro, Catalano, Carlo, Fanelli, Fabrizio, Fiocca, Fausto, Gazzetti, Marianna, Maher, Ben, Santoni, Mariangela   +6 more
core   +1 more source

MicroRNA-125b predicts clinical outcome and suppressed tumor proliferation and migration in human gallbladder cancer

Tumor Biology, 2017
We intended to investigate the functional role and clinical relevance of microRNA-125b in human gallbladder cancer. Quantitative real-time polymerase chain reaction was used to examine microRNA-125b expression in gallbladder cancer cell lines, and 79 ...
Liang Yang, Sheng Huang, Hongbin Ma, Xiaoxiong Wu, Feiling Feng   +4 more
doaj   +1 more source

Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy

Molecular Cancer, 2019
Background Gallbladder cancer is the most common biliary tract malignancy and not sensitive to chemotherapy. Autophagy is an important factor prolonging the survival of cancer cells under chemotherapeutic stress.
Qiang Cai, Shouhua Wang, Longyang Jin, Mingzhe Weng, Di Zhou, Jiandong Wang, Zhaohui Tang, Zhiwei Quan   +7 more
doaj   +1 more source

A Multiorgan Trafficking Circuit Provides Purifying Selection of Listeria monocytogenes Virulence Genes. [PDF]

, 2019
Listeria monocytogenes can cause a life-threatening illness when the foodborne pathogen spreads beyond the intestinal tract to distant organs. Many aspects of the intestinal phase of L. monocytogenes pathogenesis remain unknown.
Becattini, Simone, Louie, Alexander, Portnoy, Daniel A, Waldor, Matthew K, Zhang, Ting   +4 more
core   +2 more sources

The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]

, 2019
Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A., D'arpa F., Di Carlo P., Fasciana T., Giammanco A., Gulotta G., Rodolico V., Sergi C., Serra N.   +8 more
core   +1 more source

Acetylation stabilizes stathmin1 and promotes its activity contributing to gallbladder cancer metastasis

Cell Death Discovery, 2022
Gallbladder cancer is the most common biliary tract malignant tumor with highly metastatic characters and poor prognosis. However, the underlying mechanism remains unclear. Stathmin1 is ubiquitous phosphoprotein, regulating microtubule stabilization.
Kun Fan, Xiaojian Ni, Sheng Shen, Zijun Gong, Jiwen Wang, Yanlei Xin, Bohao Zheng, Wentao Sun, Han Liu, Tao Suo, Xiaoling Ni, Houbao Liu   +11 more
doaj   +1 more source

Gallbladder cancer: current and future treatment options

Frontiers in Pharmacology, 2023
Surgery remains the preferred treatment option for early-stage gallbladder cancer (GBC). According to the anatomical position of the primary tumor, accurate preoperative stage and strict control of surgical indications, appropriate surgical strategies ...
Yanzhao Zhou, Yanzhao Zhou, Kun Yuan, Yi Yang, Zemin Ji, Dezheng Zhou, Jingzhong Ouyang, Zhengzheng Wang, Fuqiang Wang, Chang Liu, Qingjun Li, Qi Zhang, Qiang Li, Xiao Shan, Jinxue Zhou   +14 more
doaj   +1 more source

Radical resection of advanced gallbladder cancer after gemcitabine combined with S-1 and Sintilimab chemotherapy: A case report. [PDF]

Medicine (Baltimore)
Mou J, Xu H, Zhang B, Zheng Y, Wu S, Zhu K.   +5 more
europepmc   +2 more sources