Results 11 to 20 of about 53,197 (218)

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

A Rare Presentation of Gallbladder Carcinoma Metastasis [PDF]

Journal of Clinical and Diagnostic Research, 2014
Gallbladder carcinoma is the 5th most common gastrointestinal cancer. Gallbladder cancer preferentially metastasizes to regional lymph nodes and liver parenchyma. Bone metastases from gallbladder carcinoma are rare presentation.
Sheela Chaudhari, Deepa Hatwal, Pawan Bhat   +2 more
doaj   +1 more source

Retrospective histopathologic findings of routine cholecystectomy specimens in a teaching hospital in North East India

Journal of Family Medicine and Primary Care, 2022
Background: Cholecystectomy is one of the most common general surgical operations performed worldwide. Limited data is available about the histopathological diagnoses of various gallbladder diseases in North Eastern part of India even though a higher ...
Ranendra Hajong, Kewithinwangbo Newme, Thoiba Moirangthem, Donkupar Khongwar, Arup Jyoti Baruah   +4 more
doaj   +1 more source

Incidental Gallbladder Cancer: Routine versus Selective Histological Examination After Cholecystectomy

The Surgery Journal, 2021
Background Incidental gallbladder cancer is relatively rare, with an incidence ranging between 0.19 and 5.5% of all the cholecystectomies for benign disease, and carries a poor prognosis. Currently, in the literature, there appears to be some controversy
Andrew Alabi, A D. Arvind, Nikhil Pawa, Shakir Karim, Jason Smith   +4 more
doaj   +1 more source

Prevalence of Gallbladder Cancer in Cases Presented to Tertiary Care Hospital, Retrospective Five-Year Study on Cholecystectomy Specimen [PDF]

Journal of Liaquat National Hospital, 2023
Background: The gallbladder is surgically removed in a cholecystectomy. The prevalence of gallbladder carcinoma is determined by examining cholecystectomy specimens.
Abu Sufyan, Safeena Sarfraz, Qurat ul Ain Tahir, Shahid Farooq, Madiha Arshad, Rabia Altaf   +5 more
doaj   +1 more source

MBD1 promotes the malignant behavior of gallbladder cancer cells and induces chemotherapeutic resistance to gemcitabine

Cancer Cell International, 2019
Background Methyl-CpG binding domain protein 1 (MBD1), which couples DNA methylation to transcriptional repression, has been implicated in transcriptional regulation, heterochromatin formation, genomic stability, cell cycle progression and development ...
Liu Wensheng, Zhang Bo, Hu Qiangsheng, Xu Wenyan, Ji Shunrong, Xu Jin, Ni Quanxing, Yu Xianjun, Xu Xiaowu   +8 more
doaj   +1 more source

Genetic mutational analysis of β-catenin gene affecting GSK-3β phosphorylation plays a role in gallbladder carcinogenesis: Results from a case control study

Cancer Treatment and Research Communications, 2020
This manuscript has reported different mutations of β-catenin gene in gallbladder cancer patients which affect GSK-3β phosphorylation site. Purpose: Gallbladder carcinoma (GBC) is a relatively rare and fatal cancer with poor prognosis.
Ruhi Dixit, Manoj Pandey, Sunil Kumar Tripathi, Amit Nandan Dhar Dwivedi, Vijay Kumar Shukla   +4 more
doaj   +1 more source

Neoadjuvant therapy for gallbladder cancer: current status and challenge [PDF]

Waike lilun yu shijian, 2023
Gallbladder cancer is one of highly malignant digestive system tumors with insidious symptoms, rapid progression, and poor prognosis. Although radical resective surgery is the only possible curative way for gallbladder cancer, most patients have lost the
XING Ying, CHENG Shi
doaj   +1 more source

MicroRNA-125b predicts clinical outcome and suppressed tumor proliferation and migration in human gallbladder cancer

Tumor Biology, 2017
We intended to investigate the functional role and clinical relevance of microRNA-125b in human gallbladder cancer. Quantitative real-time polymerase chain reaction was used to examine microRNA-125b expression in gallbladder cancer cell lines, and 79 ...
Liang Yang, Sheng Huang, Hongbin Ma, Xiaoxiong Wu, Feiling Feng   +4 more
doaj   +1 more source

Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy

Molecular Cancer, 2019
Background Gallbladder cancer is the most common biliary tract malignancy and not sensitive to chemotherapy. Autophagy is an important factor prolonging the survival of cancer cells under chemotherapeutic stress.
Qiang Cai, Shouhua Wang, Longyang Jin, Mingzhe Weng, Di Zhou, Jiandong Wang, Zhaohui Tang, Zhiwei Quan   +7 more
doaj   +1 more source