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Neoadjuvant therapy for gallbladder cancer: current status and challenge [PDF]
Gallbladder cancer is one of highly malignant digestive system tumors with insidious symptoms, rapid progression, and poor prognosis. Although radical resective surgery is the only possible curative way for gallbladder cancer, most patients have lost the
XING Ying, CHENG Shi
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Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Ritter, Christoph von +11 more
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Background Incidental gallbladder cancer is relatively rare, with an incidence ranging between 0.19 and 5.5% of all the cholecystectomies for benign disease, and carries a poor prognosis. Currently, in the literature, there appears to be some controversy
Andrew Alabi +4 more
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Hepatopancreatoduodenectomy –a controversial treatment for bile duct and gallbladder cancer from a European perspective [PDF]
Background: Hepatopancreatoduodenectomy (HPD) is an aggressive operation for treatment of advanced bile duct and gallbladder cancer associated with high perioperative morbidity and mortality, and uncertain oncological benefit in terms of survival.
E-AHPBA scientific and research committee
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Background Methyl-CpG binding domain protein 1 (MBD1), which couples DNA methylation to transcriptional repression, has been implicated in transcriptional regulation, heterochromatin formation, genomic stability, cell cycle progression and development ...
Liu Wensheng +8 more
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This manuscript has reported different mutations of β-catenin gene in gallbladder cancer patients which affect GSK-3β phosphorylation site. Purpose: Gallbladder carcinoma (GBC) is a relatively rare and fatal cancer with poor prognosis.
Ruhi Dixit +4 more
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Palliation in Gallbladder Cancer: The Role of Gastrointestinal Endoscopy
Gallbladder cancer is a rare malignancy burdened by poor prognosis with an estimated 5-year survival of 5% to 13% due to late presentation, early infiltration of surrounding tissues, and lack of successful treatments.
Tommaso Schepis +4 more
core +1 more source
We intended to investigate the functional role and clinical relevance of microRNA-125b in human gallbladder cancer. Quantitative real-time polymerase chain reaction was used to examine microRNA-125b expression in gallbladder cancer cell lines, and 79 ...
Liang Yang +4 more
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Background Gallbladder cancer is the most common biliary tract malignancy and not sensitive to chemotherapy. Autophagy is an important factor prolonging the survival of cancer cells under chemotherapeutic stress.
Qiang Cai +7 more
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Body size indicators and risk of gallbladder cancer: Pooled analysis of individual-level data from 19 prospective cohort studies [PDF]
Background: There are few established risk factors for gallbladder cancer beyond gallstones. Recent studies suggest a higher risk with high body mass index (BMI), an indicator of general heaviness, but evidence from other body size measures is lacking ...
Xiao-Ou Shu +77 more
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