Results 31 to 40 of about 3,048,170 (258)

Neoadjuvant therapy for gallbladder cancer: current status and challenge [PDF]

open access: yesWaike lilun yu shijian, 2023
Gallbladder cancer is one of highly malignant digestive system tumors with insidious symptoms, rapid progression, and poor prognosis. Although radical resective surgery is the only possible curative way for gallbladder cancer, most patients have lost the
XING Ying, CHENG Shi
doaj   +1 more source

Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]

open access: yes, 1994
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Ritter, Christoph von   +11 more
core   +1 more source

MBD1 promotes the malignant behavior of gallbladder cancer cells and induces chemotherapeutic resistance to gemcitabine

open access: yesCancer Cell International, 2019
Background Methyl-CpG binding domain protein 1 (MBD1), which couples DNA methylation to transcriptional repression, has been implicated in transcriptional regulation, heterochromatin formation, genomic stability, cell cycle progression and development ...
Liu Wensheng   +8 more
doaj   +1 more source

Genetic mutational analysis of β-catenin gene affecting GSK-3β phosphorylation plays a role in gallbladder carcinogenesis: Results from a case control study

open access: yesCancer Treatment and Research Communications, 2020
This manuscript has reported different mutations of β-catenin gene in gallbladder cancer patients which affect GSK-3β phosphorylation site. Purpose: Gallbladder carcinoma (GBC) is a relatively rare and fatal cancer with poor prognosis.
Ruhi Dixit   +4 more
doaj   +1 more source

Cholesterol nucleation time in gallbladder bile of patients with solitary or multiple cholesterol gallstones [PDF]

open access: yes, 1992
Patients with multiple cholesterol gallbladder stones have been found to be at a higher risk for the recurrence of gallstones after successful nonsurgical treatment than those with a solitary stone.
Ritter, Christoph von   +4 more
core   +1 more source

Treatment of Resectable Gallbladder Cancer

open access: yes, 2022
Gallbladder cancer (GBC) is the most common biliary tract cancer worldwide and its incidence has significant geographic variation. A unique combination of predisposing factors includes genetic predisposition, geographic distribution, female gender ...
Claudius Conrad   +4 more
core   +1 more source

MicroRNA-125b predicts clinical outcome and suppressed tumor proliferation and migration in human gallbladder cancer

open access: yesTumor Biology, 2017
We intended to investigate the functional role and clinical relevance of microRNA-125b in human gallbladder cancer. Quantitative real-time polymerase chain reaction was used to examine microRNA-125b expression in gallbladder cancer cell lines, and 79 ...
Liang Yang   +4 more
doaj   +1 more source

Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy

open access: yesMolecular Cancer, 2019
Background Gallbladder cancer is the most common biliary tract malignancy and not sensitive to chemotherapy. Autophagy is an important factor prolonging the survival of cancer cells under chemotherapeutic stress.
Qiang Cai   +7 more
doaj   +1 more source

Role of High total protein in gallbladder bile in the formation of cholesterol gallstones. [PDF]

open access: yes, 1991
While it is generally accepted that cholesterol supersaturation of bile is of key importance in the rapid formation of cholesterol crystals, the role of total biliary protein and pH in the pathogenesis of cholesterol gallstones is less well understood ...
Ritter, Christoph von   +3 more
core   +1 more source

Indomethacin decreases viscosity of gallbladder bile in patients with cholesterol gallstone disease [PDF]

open access: yes, 1993
There is experimental evidence that inhibition of cyclooxygenase with nonsteroidal anti-inflammatory drugs may decrease cholesterol gall-stone formation and mitigate biliary pain in gall-stone patients.
Niemeyer, A.   +8 more
core   +1 more source

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