Results 301 to 310 of about 17,313 (328)
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Gallium‐68‐labelled NOTA‐oligonucleotides: an optimized method for their preparation
Journal of Labelled Compounds and Radiopharmaceuticals, 2015One of the most essential aspects to the success of radiopharmaceuticals is an easy and reliable radiolabelling protocol to obtain pure and stable products. In this study, we optimized the bioconjugation and gallium‐68 (68Ga) radiolabelling conditions for a single‐stranded 40‐mer DNA oligonucleotide, in order to obtain highly pure and stable ...
Gijs, Marlies +8 more
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Acta Radiologica, 2014
Background Gallium-68 somatostatin receptor positron emission tomography (PET) has been used in the diagnosis of neuroendocrine tumors (NETs). The compounds often used in molecular imaging of NETs with PET are 68Ga-DOTATOC, 68Ga-DOTATATE, and 68Ga-DOTANOC. There is varying affinity to different somatostatin receptors.
Jigang, Yang +5 more
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Background Gallium-68 somatostatin receptor positron emission tomography (PET) has been used in the diagnosis of neuroendocrine tumors (NETs). The compounds often used in molecular imaging of NETs with PET are 68Ga-DOTATOC, 68Ga-DOTATATE, and 68Ga-DOTANOC. There is varying affinity to different somatostatin receptors.
Jigang, Yang +5 more
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A NEW GERMANIUM-68/GALLIUM-68 GENERATOR
Journal of Computer Assisted Tomography, 1979A germanium-gallium generator producing EDTA-free Ga-68 would permit the synthesis of a broad range of Ga-68 radiopharmaceuticals and thus facilitate the widespread application of positron tomography. We have investigated a solvent-extraction generator system producing the weak complex of Ga-68 with 8-hydroxyquinoline (Ga-68 oxine), free of EDTA.
Gary J. Ehrhardt, Michael J. Welch
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Gallium-68: A New Trend in PET Radiopharmacy
Current Radiopharmaceuticalse, 2012The most common PET radioisotopes, both in the literature and in clinical practice, are the cyclotron produced 11C and 18F, giving rise to tracers with minimal chemical changes with respect to the original biological molecule. However, the short half-life of these two radioisotopes and the relatively complex chemistry of their incorporation into the ...
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Gallium-68-labeled radiopharmaceuticals: a review
Chemical Society ReviewsThis review delves into the realm of gallium-68 (68Ga)-labeled radiopharmaceuticals.
Karan S. Tanwar, Mukesh K. Pandey
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Gallium-68-labeled macroaggregated human serum albumin, 68Ga-MAA
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, 1989A technique is described that allows labeling of commercial MAA (macroaggregated human serum albumin) kits with generator-produced 68Ga. This positron-emitting radio-pharmaceutical should serve as an effective substitute for 68Ga-albumin microspheres in PET imaging studies that require a particulate tracer of regional perfusion.
G A, Even, M A, Green
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Stable labelling of serum albumin microspheres with gallium-68
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1986A highly efficient and rapid technique for labelling serum albumin microspheres with 68Ga is described. Measurements of the in vivo stability of the radiopharmaceutical in the rabbit and the baboon show that less than 0.2% of the injected activity is eluted from the microspheres in 2 h.
B, Maziere +3 more
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Clinical indications for Gallium-68 positron emission tomography imaging
European Journal of Surgical Oncology (EJSO), 2009(68)Ga-PET imaging is showing slow but steady progress when compared to (18)F-FDG PET. The advantage of in-house preparation of (68)Ga without necessity of a cyclotron, and the new generator configuration with future possibility of freeze-dried kits would make it a promising PET agent for the future.An exhaustive literature exploration was performed ...
M U, Khan +5 more
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Increased Gallium-68 DOTATOC Uptake in Normal Thyroid Glands
Hormone and Metabolic Research, 2011Increased Ga-68 DOTATOC uptake for normal and goitrous and/or nodular thyroids has previously been reported for a small number of patients. The aim of this study was to reevaluate these preliminary findings with larger patient numbers and to determine possible variables, which might influence the quantification of Ga-68 DOTATOC uptake in normal and ...
T, Lincke +4 more
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Imaging of Prostate Cancer Using Gallium-68–Labeled Bombesin
PET Clinics, 2017Nuclear medicine can play an important role in evaluating prostate cancer combining anatomical and functional information with hybrid techniques. Various PET radiopharmaceuticals have been used for targeting specific biological markers in prostate cancer.
Ida, Sonni +2 more
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