Results 81 to 90 of about 32,729 (195)

A 52‐Week Efficacy and Safety Study of Teneligliptin, as an Add‐On to Empagliflozin and Metformin in Patients With Type 2 Diabetes Mellitus: A Randomised, Double‐Blind, Placebo‐Controlled Phase 3 Trial (TERA305 Study)

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11955-11965, December 2026.
ABSTRACT Aims To evaluate the long‐term efficacy and safety of teneligliptin add‐on in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and empagliflozin. Materials and Methods In this randomised, double‐blind, phase 3 trial, 214 patients received teneligliptin 20 mg (n = 107) or placebo (n = 107) once daily for 24 ...
Jun Sung Moon, Kyung Ah Han, Dong‐Lim Kim, Sang Yong Kim, Soo‐Kyung Kim, Bon Jeong Ku, Woo Je Lee, Tae Keun Oh, Ji A Seo, Sang‐Ah Chang, Moon‐Kyu Lee, Kyu Jeung Ahn, Chul Sik Kim, Tae Nyun Kim, Bong‐Soo Cha   +14 more
wiley   +1 more source

Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery: study protocol for a randomized controlled trial (UPGRADE trial)

BMC Gastroenterology, 2017
Background The number of bariatric interventions for morbid obesity is increasing worldwide. Rapid weight loss is a major risk factor for gallstone development.
Thomas C. C. Boerlage, Sylke Haal, L. Maurits de Brauw, Yair I. Z. Acherman, Sjoerd Bruin, Arnold W. J. M. van de Laar, Daan E. Moes, Bart A. van Wagensveld, Claire E. E. de Vries, Ruben van Veen, Ruben Schouten, Marcel G. Dijkgraaf, Paul Fockens, Victor E. A. Gerdes, Rogier P. Voermans   +14 more
doaj   +1 more source

Liver Injury Due to Hormonal Contraceptives in the Modern Era

Liver International, Volume 46, Issue 12, December 2026.
ABSTRACT Background and Aims Hormonal agents and their association with liver injury remain a concern in clinical practice. This study aimed to characterise the biochemical and clinical features of hormonal agent‐associated liver injury and compare them with a control group of age‐ and gender‐matched cases of liver injury caused by non‐hormonal drugs ...
Raj Vuppalanchi, A. Sidney Barritt, Anjali Rai, Huiman Barnhardt, Sherry Gu, Yi‐Ju Li, Naga Chalasani, for the Drug‐Induced Liver Injury Network, Naga Chalasani, Marwan Ghabril, Raj Vuppalanchi, Bob Fontana, Alisa Likhitsup, Vincent Chen, Victoria Shakhin, Paul Watkins, Sid Barritt, B. B. Behera, Jacquee Simpson, Herb Bonkovsky, Dee Faust, Andrew Stolz, Lily Dara, Neil Kaplowitz, Susan Milstein, Gina Choi, Jacqueline Nguyen, Angela Yeh, Dina Halegoua‐DeMarzio, Victor Navarro, Manish Thapar, Manisha Verma, Katrin Koy‐Pan, Verma Manisha, Cynthia Miller, Angela Pallotto, Christopher Koh, Beverly Niles, Jaha Norman, Huiman Barnhart, Matthew Baum, Jiezhun Gu, Yi‐Ju Li, Michelle McClanahan‐Crowder, Jeremy Mercer, Patricia Montana, Viviana Moreno, Eilene Pham, Hoss Rostami, Sheri Ussery, Kaye Williams, Stephanie Wu, Peter Hoffmann, Kidney Diseases, José Serrano, Jay Hoofnagle, Averell H. Sherker   +56 more
wiley   +1 more source

The Circulating Cholangiocarcinoma Protein Biomarkers CRP and MASP2 Also Predict Gallbladder Cancer Risk

International Journal of Cancer, Volume 159, Issue 10, Page 2403-2407, 15 November 2026.
ABSTRACT In a recent publication, Lapitz et al. reported differences in serum levels that predict the development of cholangiocarcinoma (CCA) in patients with primary sclerosing cholangitis prior to clinical manifestation. We examined whether these biomarkers also predict the risk of gallbladder cancer (GBC) in European prospective plasma samples from ...
Linda Zollner, Jeroen Krijgsveld, Dominique Scherer, Justo Lorenzo Bermejo, on behalf of the EULAT Eradicate GBC Consortium   +4 more
wiley   +1 more source

Gallstone Disease [PDF]

BMJ, 1968
openaire   +5 more sources

Rapid Progression of Acute Acalculous Cholecystitis to Gangrenous Cholecystitis in an Initially Non‐Critically Ill Patient: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Acute acalculous cholecystitis (AAC) is not confined to the critically ill and may behave like calculous disease. A 65‐year‐old hypertensive man with localized, stone‐free cholecystitis deteriorated on hospital Day 4 with peritonism, acidosis, and acute kidney injury.
Rami Y. Adam, Sami J. Eldein, Mahmoud M. Mahmoud, Mohamed S. M. Elshikhawoda, Omer Musa, Faris Abdon   +5 more
wiley   +1 more source

Fatty Acid Oxidation Disorders Detected by Newborn Screening: Clinical, Biochemical and Genetic Spectrum in a Single‐Center Cohort

JIMD Reports, Volume 67, Issue 6, November 2026.
ABSTRACT Newborn screening (NBS) has significantly improved early detection and survival in fatty acid oxidation disorders (FAODs). However, the expanding phenotypic spectrum challenges prognostic stratification, and long‐term morbidity remains incompletely characterized.
Elena Martín‐Hernández, Delia Barrio‐Carreras, María Martín‐Cazaña, Luis Miguel García‐Cárdaba, Carmen Martín‐Fernández, Patricia Pérez‐Mohand, Teresa Hernández Chamorro, Berta Zamora Crespo, Pedro Ruiz‐Sala, Patricia Alcaide Alonso, Pilar Quijada‐Fraile   +10 more
wiley   +1 more source

Biliary Abnormality on Imaging During Lenvatinib Plus Hepatic Arterial Infusion Chemotherapy With Cisplatin for Hepatocellular Carcinoma: A Pilot Descriptive Study

Hepatology Research, Volume 56, Issue 11, Page 1575-1585, November 2026.
ABSTRACT Aim To evaluate the frequency, imaging characteristics, associated factors, and clinical significance of biliary abnormalities on imaging in patients receiving lenvatinib (LEN) plus cisplatin hepatic arterial infusion chemotherapy (HAIC) for hepatocellular carcinoma (HCC).
Hirohito Osanai, Kazuto Kozaka, Takashi Matsubara, Norihide Yoneda, Takahiro Ogi, Kenichiro Okumura, Atsushi Takamatsu, Azusa Kitao, Shintaro Yagi, Taro Yamashita, Satoshi Kobayashi   +10 more
wiley   +1 more source

Association between triglyceride glucose index-related indices with gallstone disease among US adults

Lipids in Health and Disease
Background Triglyceride glucose (TyG) index combined with obesity-related indicators [triglyceride glucose-body mass index (TyG-BMI), triglyceride glucose-waist to height ratio (TyG-WHtR), triglyceride glucose-waist circumference (TyG-WC)], represents ...
Chang Fu, Xiaocong Li, Yongxin Wang, Junhong Chen, Yibo Yang, Kai Liu   +5 more
doaj   +1 more source

Association between plant-based dietary index and gallstone disease: A cross sectional study from NHANES.

PLoS ONE
BackgroundThe relationship between plant-based diets and gallstone disease has been debated. This study aimed to shed light on the association between plant-based dietary index and the risk of developing gallstone disease.MethodsEligible participants ...
Luyang Li, Chengli Liu, Tian Xia, Haoming Li, Jun Yang, Meng Pu, Shuhan Zhang, Yingbo Ma, Tao Zhang   +8 more
doaj   +1 more source