Results 61 to 70 of about 44,009 (270)

Inhibition of growth of hepatocellular carcinoma by co-delivery of anti-PD-1 antibody and sorafenib using biomimetic nano-platelets

BMC Cancer
Background Traditional nanodrug delivery systems have some limitations, such as eliciting immune responses and inaccuracy in targeting tumor microenvironments.
Xuanbo Da, Bangping Cao, Jiantao Mo, Yukai Xiang, Hai Hu, Chen Qiu, Cheng Zhang, Beining Lv, Honglei Zhang, Chuanqi He, Yulong Yang   +10 more
doaj   +1 more source

Effect of early-life exposure to environmental risk factors on adult MASLD: Insights from DOHaD perspective

生物医学转化
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease globally, affecting approximately 30% of the adult population.
Zhang Hongchao, Francisco Javier Cubero, Zhao Gang, Xu Jin, Liu Qian, Shao Wentao, Gu Aihua   +6 more
doaj   +1 more source

Triglyceride‐Related Indices and Risk of Acute Pancreatitis: A Prospective Study in UK Biobank

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Triglyceride‐related indices, including triglyceride‐glucose (TyG), TyG related to body mass index (TyG‐BMI), TyG related to waist circumference (TyG‐WC), TyG related to waist‐to‐height ratio (TyG‐WHtR), atherogenic index of plasma (AIP), cardiometabolic index (CMI), visceral adiposity index (VAI), and lipid accumulation product (LAP), are ...
Jing‐Bo Li, Yu‐Jiao Zhu, Yang‐Jie Liao, Jia‐Yi Wang   +3 more
wiley   +1 more source

A Role of the Bile Salt Receptor FXR in Atherosclerosis [PDF]

, 2010
This study reviews current insights into the role of bile salts and bile salt receptors on the progression and regression of atherosclerosis. Bile salts have emerged as important modifiers of lipid and energy metabolism.
Groen, A.K., Hageman, J., Herrema, H.J., Kuipers, F.   +3 more
core   +3 more sources

Maternal smoking during pregnancy is risk factor for gallbladder disease in offspring during adulthood: a prospective study from UK Biobank

Annals of Hepatology, 2021
s: Introduction and objectives: Gallbladder disease is a common disease with high prevalence. Majority of gallbladder disease is due to gallstone.
Wenxiang Li, Jingjia Liang, Wentao Shao, Cheng Xu, Jin Xu, Zhaoyan Jiang, Aihua Gu   +6 more
doaj   +1 more source

Association of diverse bacterial communities in human bile samples with biliary tract disorders: a survey using culture and polymerase chain reaction-denaturing gradient gel electrophoresis methods [PDF]

, 2016
Bacterial infection is considered a predisposing factor for disorders of the biliary tract. This study aimed to determine the diversity of bacterial communities in bile samples and their involvement in the occurrence of biliary tract diseases. A total of
Alebouyeh, M., Alizadeh, A.H.M., Majidi, M.R.S., Sherafat, S.J., Tajeddin, E., Zali, M.R.   +5 more
core   +1 more source

Genetics of gallstone disease [PDF]

European Journal of Clinical Investigation, 2018
AbstractBackgroundGallstone disease (GD) belongs to the most frequent disorders in gastroenterology and causes high costs in our health‐care systems. Gallstones are uncommon in children but frequent in adults, in particular in women, and are triggered by exogenous risk factors.
Charlotte Rebholz, Marcin Krawczyk, Frank Lammert   +2 more
openaire   +2 more sources

Quality of life and healthcare resource utilization among adult patients with short bowel syndrome: A mixed‐methods study leveraging an integrated database

Nutrition in Clinical Practice, EarlyView.
Abstract Background Short bowel syndrome (SBS) is a chronic condition requiring parenteral nutrition (PN) support and multidisciplinary management. However, disparities in access to care and standardized treatment pathways, in addition to economic burden, remain considerable for patients.
Deborah Kuk, Brian Po‐Han Chen, Megan Gower, Michelle Kirby, Brian Terreri, Josh Feldman, Maggie McCue, Manpreet S. Mundi   +7 more
wiley   +1 more source

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes [PDF]

, 2016
Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. Methods In this double-blind trial, we randomly assigned patients with type 2 diabetes
Bergenstal, RM, Brown-Frandsen, K, Buse, JB, Daniels, GH, Kristensen, P, LEADER Steering Committee on behalf of the LEADER Trial Investigators, Mann, JF, Marso, SP, Nauck, MA, Nissen, SE, Pocock, S, Poulter, NR, Ravn, LS, Steinberg, WM, Stockner, M, Zinman, B   +15 more
core   +1 more source

Association of three common single nucleotide polymorphisms of ATP binding cassette G8 gene with gallstone disease: a meta-analysis. [PDF]

PLoS ONE, 2014
In this study, we evaluated the association between these polymorphisms and gallstone disease using meta-analysis and compared the hepatic ABCG5/G8 mRNA expression and biliary lipids composition in patients with different genotypes of T400K and Y54C.Data
Zhao-Yan Jiang, Qu Cai, Er-Zhen Chen
doaj   +1 more source