Results 101 to 110 of about 77,106 (282)
The use of different types of networks, alone and in combination, for drug target identification
British Journal of Pharmacology, EarlyView.Current therapeutic approaches often focus on targeting clinical symptoms or peripheral phenotypes rather than the underlying molecular mechanisms, or endophenotypes, that drive diseases. While symptom‐based drugs can alleviate discomfort, they do not necessarily alter disease progression and may overlook opportunities for prevention or early ...
Paolo Parini
wiley +1 more source
World Journal of Gastroenterology, 2014 Gallstones occur in about one third of the patients having liver cirrhosis. Pigment gallstones are the most frequent type, while cholesterol stones represent about 15% of all stones in cirrhotics.
M. Acalovschi
semanticscholar +1 more source
BMC Public HealthBackground Gallstones are a common hepatobiliary disorder. It is unclear whether cardiometabolic index (CMI) is associated with gallstones. The purpose of this study was to examine the association between CMI levels and gallstone prevalence among US ...
Jing Zheng +7 more
doaj +1 more source
Beyond Carrier Status: CFTR Heterozygosity as an Overlooked Clinical Risk Factor for Pancreatitis
Clinical Genetics, EarlyView.CFTR carrier status detected via prenatal screening is associated with increased pancreatitis risk in women, but clinical recognition remains low. Integrating carrier results into electronic health records may enhance personalized care and aid in early diagnosis. ABSTRACT This study assessed the effect of CFTR pathogenic variant status, detected during
Lucas D. Richter +3 more
wiley +1 more source
BMC Gastroenterology, 2014 BackgroundWhether non-alcoholic fatty liver disease (NAFLD) is a risk factor for gallstones remains uncertain. Few longitudinal or cohort studies have been used to identify this relationship.
Jia Liu +8 more
semanticscholar +1 more source
The association between triglyceride-glucose index and gallstones: NHANES 2017-2020
Frontiers in EndocrinologyObjectsIt remains unclear whether the triglyceride-glucose (TyG) index has correlations with gallstones. This study aimed to investigate the association between TyG index and gallstones.MethodsData was obtained from the 2017-2020 National Health and ...
Li Gong +8 more
doaj +1 more source
Association of diverse bacterial communities in human bile samples with biliary tract disorders: a survey using culture and polymerase chain reaction-denaturing gradient gel electrophoresis methods [PDF]
, 2016 Bacterial infection is considered a predisposing factor for disorders of the biliary tract. This study aimed to determine the diversity of bacterial communities in bile samples and their involvement in the occurrence of biliary tract diseases. A total of
Alebouyeh, M. +5 more
core +1 more source
Prevalence of and risk factors for gallstones in Uighur and Han Chinese.
World Journal of Gastroenterology, 2014 AIM To perform a single-centre survey of the prevalence of and possible risk factors for gallstones in Uighur and Han Chinese. METHODS Complete medical data for 9455 patients were collected from the medical centre of our hospital, and the overall ...
Li Zhu +4 more
semanticscholar +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Aims Semaglutide, a GLP‐1 receptor agonist, has shown efficacy in promoting weight loss. However, limited data exist on its impact on lean mass, muscle function, and metabolic adaptations. The SEMALEAN study aims to evaluate these parameters in patients with obesity treated with Semaglutide (2.4 mg).
Mathieu Alissou +18 more
wiley +1 more source