Results 101 to 110 of about 89,842 (291)

Prevalence of and risk factors for gallstones in Uighur and Han Chinese.

World Journal of Gastroenterology, 2014
AIM To perform a single-centre survey of the prevalence of and possible risk factors for gallstones in Uighur and Han Chinese. METHODS Complete medical data for 9455 patients were collected from the medical centre of our hospital, and the overall ...
Li Zhu, Aikebaier Aili, Cheng Zhang, Aili Saiding, Kelimu Abudureyimu   +4 more
semanticscholar   +1 more source

Iron overload and morbidities in Chinese with non‐transfusion‐dependent thalassaemia

British Journal of Haematology, EarlyView.
A cross‐sectional study in Hong Kong included 109 adult and paediatric Chinese patients with non‐transfusion dependent thalassaemia (NTDT). The study found significant chronic health issues in 52% of patients. More severe disease was observed in patients with non‐deletional α‐thalassaemia intermedia, β‐thalassaemia intermedia, advanced age and history ...
Wing‐yan Leung, Tracy Yuen‐han Lee, Yu‐yan Hwang, Jasmine Tsz‐man Lee, Chun‐Fung Sin, Sio‐peng Mok, Chung‐yin Ha, Allen Li, Wendy Wai‐man Lam, Man‐fung Yuen, Yok‐lam Kwong, Dorine W. Swinkels, Coby M. Laarakkers, Daniel Ka‐leung Cheuk, Godfrey Chi‐fung Chan, Chak‐ho Li, Yiu‐fai Cheung, Chi Chiu So, Shau‐yin Ha, Anthony Pak‐yin Liu   +19 more
wiley   +1 more source

Positive association between cardiometabolic index and gallstones, with greater impact on women and those younger than 50 years: the NHANES 2017–2020 cross-sectional study

BMC Public Health
Background Gallstones are a common hepatobiliary disorder. It is unclear whether cardiometabolic index (CMI) is associated with gallstones. The purpose of this study was to examine the association between CMI levels and gallstone prevalence among US ...
Jing Zheng, Huqiang Dong, Hongli Wan, Qingye Yang, Shujuan Xu, Tingting Hu, Chang Fu, Keyun Cheng   +7 more
doaj   +1 more source

The use of different types of networks, alone and in combination, for drug target identification

British Journal of Pharmacology, EarlyView.
Current therapeutic approaches often focus on targeting clinical symptoms or peripheral phenotypes rather than the underlying molecular mechanisms, or endophenotypes, that drive diseases. While symptom‐based drugs can alleviate discomfort, they do not necessarily alter disease progression and may overlook opportunities for prevention or early ...
Paolo Parini
wiley   +1 more source

The association between triglyceride-glucose index and gallstones: NHANES 2017-2020

Frontiers in Endocrinology
ObjectsIt remains unclear whether the triglyceride-glucose (TyG) index has correlations with gallstones. This study aimed to investigate the association between TyG index and gallstones.MethodsData was obtained from the 2017-2020 National Health and ...
Li Gong, Shujin Fan, Shujin Fan, Zhenfei Peng, Zeyao Chen, Yuzhou Liu, Yinluan Huang, Chaofan Wang, Chunli Piao   +8 more
doaj   +1 more source

Visualization of Extracellular Matrix Components within Sectioned Salmonella Biofilms on the Surface of Human Gallstones

PLoS ONE, 2014
Chronic carriage of Salmonella Typhi is mediated primarily through the formation of bacterial biofilms on the surface of cholesterol gallstones.
Joanna M. Marshall, A. Flechtner, K. L. La Perle, J. Gunn   +3 more
semanticscholar   +1 more source

Beyond Carrier Status: CFTR Heterozygosity as an Overlooked Clinical Risk Factor for Pancreatitis

Clinical Genetics, EarlyView.
CFTR carrier status detected via prenatal screening is associated with increased pancreatitis risk in women, but clinical recognition remains low. Integrating carrier results into electronic health records may enhance personalized care and aid in early diagnosis. ABSTRACT This study assessed the effect of CFTR pathogenic variant status, detected during
Lucas D. Richter, Douglas M. Ruderfer, Josh F. Peterson, Lisa A. Bastarache   +3 more
wiley   +1 more source

The Growing Burden of Obesity: Addressing a Global Public Health Challenge

United European Gastroenterology Journal, EarlyView.
Patrizia Burra, Elvira Verduci, Jorge Amil Dias, Maria Buti, Anna Carboni, Coskun Ozer Demirtas, Pierluigi Fracasso, Daniel Hartman, Andrea Laghi, Patrick Michl, Shira Zelber‐Sagi, UEG Public Affairs Group   +11 more
wiley   +1 more source

Glycemic therapies and the risk of gastrointestinal adverse events in veterans with type 2 diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To compare the risk of gastrointestinal adverse events in new users of glucagon‐like peptide‐1 receptor agonists (GLP‐1RA), sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) and insulin glargine. Materials and Methods We conducted an active comparator, new user design study in veterans with type 2 diabetes who initiated one of these drug
Amara Sarwal, Ravinder Singh, Guo Wei, Jincheng Shen, McKenna Nevers, Sydney E. Hartsell, Catherine G. Derington, Augustine Takyi, Akhil R. Chakravartula, Niharika Katkam, Robert E. Boucher, Stavros G. Drakos, Tom Greene, Srinivasan Beddhu   +13 more
wiley   +1 more source

Acidosis is associated with lower insulin sensitivity and incident type 2 diabetes in indigenous Americans: A prospective cohort study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aim Whether markers of acid accumulation [decreased plasma bicarbonate, increased anion gap (AG) and corrected anion gap (CAG)] are associated with insulin sensitivity and alter diabetes risk is unclear. We aimed to examine the association of these markers with the gold‐standard measure of insulin sensitivity and incident type 2 diabetes ...
Andrés M. Treviño‐Alvarez, Tomás Cabeza de Baca, Emma J. Stinson, Marci E. Gluck, Paolo Piaggi, Jonathan Krakoff, Douglas C. Chang   +6 more
wiley   +1 more source