Results 81 to 90 of about 45,875 (230)

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

A Chinese X‐Linked Adrenoleukodystrophy Patient With Atypical Clinical Symptoms Contained an Undefined ABCD1 Mutation—A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT X‐linked adrenoleukodystrophy (X‐ALD) is a genetic peroxisome disorder linked to ABCD1 mutation, characterized by rapid and complex clinical symptoms. We here report a case of X‐ALD manifesting solely as dysarthria, associated with an undefined mutation in the ABCD1 gene, underscoring the necessity of atypical clinical symptoms in X‐ALD ...
Fu‐Qing Zhang, Zhuoran Zhang, Dongliang Wang, Ying Yang, Xin Li   +4 more
wiley   +1 more source

Mouret, Dubois, and Perissat : the laparoscopic breakthrough in Europe (1987-1988) [PDF]

, 1999
In the late 1980s, laparoscopy was essentially a gynecologist's tool. One of the French private surgeons, Phillipe Mouret of Lyon, shared his surgery practice with a gynecologist and thus had access to both laparoscopic equipment and to patients ...
Litynski, Grzegorz S.
core  

When Silence Speaks: A Perforated Hepatic Cyst, Intact Omental Cyst, and Cholelithiasis

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A 39‐year‐old man from an echinococcosis‐endemic region presented with acute left upper quadrant pain. Imaging revealed cholelithiasis, a hepatic and a large abdominal cystic masses, and significant free peritoneal fluid. Urgent laparotomy unexpectedly disclosed three concurrent pathologies: chronic calculous cholecystitis, a perforated ...
Mohadese Hematian, Pooneh Torabi, Mahsa Sayyari, Rahem Rahmati, Mohammad Reza Ghanbari Boroujeni, Rasoul Rahimi   +5 more
wiley   +1 more source

Association between weekend catch-up sleep and gallstone disease in US adults: a cross-sectional study from NHANES 2017–2020

Frontiers in Public Health
BackgroundGallstones are the most prevalent cause of hospitalization among digestive disorders. For humans, sleep is an essential physiological function.
Jianwei Cao, Weishuai Zhang, Jixuan Yi, Yang Zhang, Xiaoyan Tong, Xiangnan Zhu   +5 more
doaj   +1 more source

Abdominal Symptoms and Incident Gallstones in a Population Unaware of Gallstone Status

Canadian Journal of Gastroenterology and Hepatology, 2016
Introduction. Symptoms associated with newly formed gallstones have never been studied in a population unaware of their gallstones. The objective of this population-based cohort study was to determine which debut of abdominal symptoms was associated with
Daniel Mønsted Shabanzadeh, Lars Tue Sørensen, Torben Jørgensen   +2 more
doaj   +1 more source

Recovery After Critical Illness: A Meta‐Ethnography of Patient, Family and Staff Perspectives

Journal of Advanced Nursing, Volume 82, Issue 5, Page 4876-4894, May 2026.
ABSTRACT Aim To synthesise primary qualitative studies reporting experiences of post‐hospital recovery for critical care survivors, their family and the healthcare professionals supporting them with a particular focus on physical impairment. Design The review was conducted through a meta‐ethnography using the seven stages of Noblit and Hare.
Elizabeth King, Owen Gustafson, Annabel Williams, Francine Toye, Mark Williams, Sarah Vollam   +5 more
wiley   +1 more source

Spontaneous extrusion of gallstones after percutaneous drainage [PDF]

, 2017
There have been reports of late discharge of gallstones through operative wounds after spillage into the peritoneal cavity during laparoscopic cholecystectomy and after the development of spontaneous cholecystocutaneous fistulae.
Hariharan, D., Lobo, Dileep N.
core   +2 more sources

High cholesterol absorption efficiency interferes with bile acid metabolism and cholesterol elimination from the body

Journal of Internal Medicine, Volume 299, Issue 5, Page 628-638, May 2026.
Abstract Background Elevated low‐density lipoprotein (LDL) cholesterol causes atherosclerotic cardiovascular diseases. Variables of whole‐body cholesterol metabolism, for example, high cholesterol absorption efficiency, might also be atherogenic, whereas the role of bile acids is controversial.
Piia Simonen, Ingmar Wester, Jyri Lommi, Juha Sinisalo, Helena Gylling   +4 more
wiley   +1 more source

Positive association between cardiometabolic index and gallstones, with greater impact on women and those younger than 50 years: the NHANES 2017–2020 cross-sectional study

BMC Public Health
Background Gallstones are a common hepatobiliary disorder. It is unclear whether cardiometabolic index (CMI) is associated with gallstones. The purpose of this study was to examine the association between CMI levels and gallstone prevalence among US ...
Jing Zheng, Huqiang Dong, Hongli Wan, Qingye Yang, Shujuan Xu, Tingting Hu, Chang Fu, Keyun Cheng   +7 more
doaj   +1 more source