Results 71 to 80 of about 33,366 (248)

Defining Age to Screen and Real‐World Effectiveness for Early‐Onset Colorectal Cancer

Cancer Science, EarlyView.
Implementation of a RAP‐based risk‐adapted screening strategy enables personalized screening initiation, with benefits comparable to those observed in the current 50–54‐year age group.
Le Wang, Yu Qiu, Xuechen Chen, Weimiao Wu, Chen Zhu, Weiwei Chen, Tingting Pan, Dong Hang, Lingbin Du   +8 more
wiley   +1 more source

Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination Survey

BMC Gastroenterology
Background The weight-adjusted-waist index (WWI) is a novel obesity index, and gallstones are associated with obesity. This study aimed to investigate the possible relationship between WWI and gallstones. Methods The datasets from the National Health and
Si-Hua Wen, Xin Tang, Tao Tang, Zheng-Rong Ye   +3 more
doaj   +1 more source

Genetic Spectrum of Cholestasis in Tunisia and Diagnostic Yield of Next‐Generation Sequencing: Case Series of 70 Patients

Clinical Genetics, EarlyView.
Genetic hepatic cholestasis: NGS diagnostic yield. Over a 10‐year period, NGS (gene panel/WES) established a genetic diagnosis in 70% of 66 families with hepatic cholestasis, with a molecular yield of 62%. ABCB11 was the most mutated gene, and PFIC Type 2 was the leading diagnosis, underscoring the critical role of NGS in guiding genetic counseling and
Amal Abdmouleh, Houweyda Jilani, Imen Rejeb, Syrine Hizem, Nicolas Pottier, Romain Larrue, Wendy Arondal, Lucie Hanquet, Rania Benrabeh, Olfa Bouyahia, Sonia Mazigh, Yasmina Elaribi, Lamia Benjemaa   +12 more
wiley   +1 more source

Relative fat mass as a predictor of gallstones: insights from national health and nutrition examination survey data

Lipids in Health and Disease
Background Gallstones have been linked to obesity. Relative fat mass (RFM) has emerged as a novel obesity index that more precisely represents the body fat distribution.
Xiaochun Lin, Hao Lin, Jing Xu, Shouxing Yang, Lei Miao   +4 more
doaj   +1 more source

Incretin‐Based Therapies as Cardiometabolic Interventions: Outcome Hierarchy, Receptor‐Network Pharmacology and Phenotype‐Based Clinical Positioning

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Incretin‐based pharmacotherapy was initially developed to improve glucose‐dependent insulin secretion and glycaemic control in type 2 diabetes, but its clinical interpretation has expanded substantially with cardiovascular outcome trials, kidney outcome data, obesity studies and next‐generation polyagonist development.
Ferenc Sztanek, Hajnalka Lőrincz, Mariann Harangi, Attila Csaba Nagy   +3 more
wiley   +1 more source

Triglyceride-Glucose Index is a Reliable Predictor of Metabolic Disorder in Gallstones [PDF]

Objective: The risk of gallstones is increased in fatty liver, overweight, and metabolic syndrome. The hyperinsulinemic-euglycemic clamp method is considered the best method for insulin resistance (IR); but it is a time consuming and expensive procedure.
Zeynep ERGENÇ, Erkan AKSOY, Hasan ERGENÇ, Özlem KARACA OCAK   +3 more
core   +1 more source

Biliary Abnormality on Imaging During Lenvatinib Plus Hepatic Arterial Infusion Chemotherapy With Cisplatin for Hepatocellular Carcinoma: A Pilot Descriptive Study

Hepatology Research, EarlyView.
ABSTRACT Aim To evaluate the frequency, imaging characteristics, associated factors, and clinical significance of biliary abnormalities on imaging in patients receiving lenvatinib (LEN) plus cisplatin hepatic arterial infusion chemotherapy (HAIC) for hepatocellular carcinoma (HCC).
Hirohito Osanai, Kazuto Kozaka, Takashi Matsubara, Norihide Yoneda, Takahiro Ogi, Kenichiro Okumura, Atsushi Takamatsu, Azusa Kitao, Shintaro Yagi, Taro Yamashita, Satoshi Kobayashi   +10 more
wiley   +1 more source

Adaptations of glucagon‐like peptide‐1 receptor agonist‐induced weight loss, drivers of weight regain and future directions of therapeutics

The Journal of Physiology, EarlyView.
Abstract figure legend During GLP‐1RA treatment reduced appetite and energy intake, delayed gastric emptying, decreased visceral fat mass and improved glycaemic control contribute to weight loss. After treatment cessation these benefits are partially or completely reversed, resulting in weight regain, accompanied by increased appetite and energy intake,
Camille E. M. Piguet, Rosie Nucci, Jacqueline L. Beaudry   +2 more
wiley   +1 more source

Associations between Life's Essential 8 and gallstones among US adults: A cross-sectional study from NHANES 2017-2018.

PLoS ONE
BackgroundCardiovascular illness and gallstones are closely related. Our goal was to determine whether gallstones and the updated LE8 score, which measures cardiovascular health among US adults, are related.Methods3,570 adults participated in the 2017 ...
Ting Wang, Ruijie Xie, Cong Jiang, Lanyu Chen   +3 more
doaj   +1 more source

A Study of Gallstones Disease incidence in Babylon's Province population

مجلة الكوفة الطبية, 2013
Background :There are multiple disorders affecting the biliary system . Malignancies,congenital anomalies, dysfunctional disorders, infections, strictures and gallstones formation are some of the spectrum of diseases affecting the biliary system.
Mahmoud Al-Mukhtar
doaj   +1 more source