Results 141 to 150 of about 33,366 (248)
Prevalence of pigment gallstones in sheep.
In a survey of 666 sheep at a slaughterhouse, gallstones (concretions with a diameter greater than or equal to 1 mm) were found in the gallbladder of 50 sheep (7.5%), sludge (concretions with a diameter less than 1 mm) was found in 9 sheep (1.4%), and ...
Guerra V +6 more
core
ABSTRACT Drug Combinations offer increased therapeutic efficacy and reduced toxicity compared with single agents. Understanding a drug combination's mechanisms of action (MoA) can provide important insights into therapeutic efficacy. The MoA of many FDA‐approved drugs, however, often remains unclear.
Rui‐Sheng Wang +5 more
wiley +1 more source
This study provides novel insights into the metabolic correlates of epigenetic aging biomarkers and underscores the potential of metabolomics‐informed metrics of epigenetic aging as informative indicators of physiological decline and lifestyle effects.
Xunying Zhao +20 more
wiley +1 more source
Socioeconomic Status, Alcohol Use, and Mortality: Results From a Prospective Cohort Study
This study examines associations of income and education, self‐reported alcohol use and alcohol biomarkers with all‐cause mortality using data from the Study of Health in Pomerania (SHIP). We observed a social gradient that was attenuated, but not fully explained by alcohol use, biomarkers, and further risk factors.
Ida Butovetsky +6 more
wiley +1 more source
ABSTRACT Aims Orforglipron is a novel small‐molecule, once daily oral non‐peptide GLP‐1 receptor agonist. The hepatic safety profile in adults with obesity or overweight and/or type 2 diabetes (T2D) across seven orforglipron Phase 3 clinical trials was assessed.
Sean Wharton +5 more
wiley +1 more source
Abnormal gallbladder emptying in patients with gallstones.
In this study, gallbladder and gastric emptying were compared in 15 normal subjects and 15 patients with gallstones. A noninvasive technique which used two gamma-emitting radiopharmaceutical agents to image the gallbladder and stomach simultaneously was ...
Rock, E +3 more
core +1 more source
Aims The aim of the research was to look into the connection between the occurrence of gallstones in adult US citizens and lipid accumulation products (LAP). Methods We conducted a cross-sectional study of 3,582 U.S.
Huimin Wang +3 more
doaj +1 more source
ABCG2 and ABCC2 Expression Levels and Their Relationship With Disease Severity in Acute Pancreatitis
ABSTRACT The aim of this study was to evaluate the expression levels of ABCG2 and ABCC2, members of the ATP‐binding cassette (ABC) transporter gene family, in patients with acute pancreatitis and to investigate their potential associations with disease presence as well as clinical and radiological disease severity.
Süleyman Baş +7 more
wiley +1 more source
Treatment Goals for Primary Biliary Cholangitis, an Australian Perspective
ABSTRACT Primary biliary cholangitis (PBC) is an autoimmune liver disease that targets the small intrahepatic bile ducts with diagnosis based on elevated serum alkaline phosphatase (ALP) levels and the presence of anti‐mitochondrial antibodies. Untreated, it may run a progressive course to cirrhosis and hepatic decompensation, at which point liver ...
Simone I. Strasser +6 more
wiley +1 more source

