Results 61 to 70 of about 92,020 (317)

A Complex Case of Cholestasis in a Patient with ABCB4 and ABCB11 Mutations [PDF]

open access: yes, 2018
The low-phospholipid-associated cholelithiasis (LPAC) syndrome is a form of symptomatic cholelithiasis occurring in young adults, characterized by recurrence of symptoms after cholecystectomy and presence of hepatolithiasis.
Anapaz, V   +7 more
core   +1 more source

Pigment Gallstones

open access: yesGastroenterology, 1977
Pigment gallstones are defined as any dark brown-to-black stone, consisting of calcium salts of bilirubin, phosphate, carbonate and other anions, and can be separated into carbonate- and noncarbonate-containing groups. Pigment stones predominate in the rural Orient, in cirrhosis, and in elderly United States patients undergoing cholecystectomy ...
R D, Soloway, B W, Trotman, J D, Ostrow
openaire   +2 more sources

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi   +2 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Efficacy and safety of endoscopic laser lithotripsy and lithotomy through the lumen-apposing metal stent for giant gallbladder stones

open access: yesVideoGIE, 2020
Background and Aims: EUS-guided gallbladder drainage has been increasingly applied for acute cholecystitis in high-risk surgical patients. In cases of EUS-guided gallbladder drainage with lumen-apposing metal stents (LAMSs), endoscopic retrieval of ...
Wei Wang, MD   +5 more
doaj   +1 more source

Increased Risk of Asymptomatic Gallstones in Patients With Ulcerative Colitis [PDF]

open access: yesIntestinal Research, 2015
Background/AimsThe relationship between Crohn's disease and gallstones is established. However, the prevalence and risk factors for gallstones in patients with ulcerative colitis (UC) are not yet well understood. The aim of this study was to evaluate the
Jung Hoon Ha   +11 more
doaj   +1 more source

Approach to the Diagnosis and Management of Gallstones

open access: yesThe Korean Journal of Gastroenterology, 2023
Gallstones are relatively common in the general population, and the clinical presentation is asymptomatic in most patients or has a benign course, such as biliary colic or vague gastrointestinal symptoms.
Kwang Hyun Chung
doaj   +1 more source

Pancreatitis following Olanzapine Therapy: A Report of Three Cases [PDF]

open access: yes, 2007
CONTEXT: Atypical antipsychotic agents (clozapine, olanzapine) have been linked to metabolic effects and acute pancreatitis. CASE REPORT: We reviewed the inpatient and outpatient records of three patients who developed acute pancreatitis while being ...
Azar, Riad   +3 more
core   +4 more sources

Quality of life and healthcare resource utilization among adult patients with short bowel syndrome: A mixed‐methods study leveraging an integrated database

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Short bowel syndrome (SBS) is a chronic condition requiring parenteral nutrition (PN) support and multidisciplinary management. However, disparities in access to care and standardized treatment pathways, in addition to economic burden, remain considerable for patients.
Deborah Kuk   +7 more
wiley   +1 more source

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