Results 171 to 180 of about 194,492 (310)

From Bored Games to Board Games: Student-Driven Game Design in the Virtual Classroom. [PDF]

J Microbiol Biol Educ, 2021
Heim AB, Holt EA.
europepmc   +1 more source

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control. [PDF]

ACS Cent Sci, 2021
Lucchi R, Bentanachs J, Oller-Salvia B.
europepmc   +1 more source

Bioinspired Mechanically Robust Organic–Inorganic Hybridized Bio‐Adhesives With up to 50% Inorganic Components by Bi‐Continuous Phase Engineering

Advanced Functional Materials, EarlyView.
A robust plant protein adhesive was prepared by fabricating a bi‐continuous organic–inorganic hybrid structure. Compared with traditional organic–inorganic hybrid adhesives, the addition amount of inorganic phase is increased from 0.2%–3.0% to 50%, and the strength and toughness are increased by 6 and 121 times, respectively.
Zheng Liu, Wenlong Luo, Xu Yang, Xin Zhang, Yuru Zhu, Jingchao Li, Jianzhang Li, Jing Luo, Zhezhe Zhou, Pingan Song, Qiang Gao   +10 more
wiley   +1 more source

Computer Chess Game Colossus 4 Chess

, 2010
Computer chess game for use with the BBC. BBC model 'B', 'B+' and Master disk (contains two disks) and instruction manual. Maker: CDS Software. Date: 1980 - 1989 - from the The Betty Smithers Design Collection at Staffordshire University.
The Betty Smithers Design Collection at Staffordshire University, Staffordshire University   +1 more
core  

Game design as a STEM pedagogy. [PDF]

J Microbiol Biol Educ
Fouilloux CA, Compton JS, Naing N, Anderson M, Hite JL.   +4 more
europepmc   +1 more source

Tabletop Board Game Elements and Gamification Interventions for Health Behavior Change: Realist Review and Proposal of a Game Design Framework. [PDF]

JMIR Serious Games, 2021
Epstein DS, Zemski A, Enticott J, Barton C.   +3 more
europepmc   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

The M.A.G.I.C. framework for mHealth development: applying game design principles from 'Magic: The Gathering'. [PDF]

Front Psychol
Broussard J, Fleet J, McBride J, Brock S, LeBrun J, Miller M, Wulfert E.   +6 more
europepmc   +1 more source

Mobile Game Design Guide to Improve Gaming Experience for the Middle-Aged and Older Adult Population: User-Centered Design Approach. [PDF]

JMIR Serious Games, 2021
Lee S, Oh H, Shi CK, Doh YY.
europepmc   +1 more source