Results 71 to 80 of about 123,097 (350)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Too Human versus the enthusiast press: Video game journalists as mediators of commodity value
Transformative Works and Cultures, 2009 This article examines the role of mediators in the production of commodity value, arguing that there is a rise in a kind of immaterial labor, shaped by contemporary conditions of late capitalism, that functions explicitly as a mediating force.
Rebecca Carlson
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Holistic game development curriculum
SIGGRAPH ASIA 2016 Symposium on Education, 2016 This article discusses the design and implementation of a holistic game development curriculum. We focus on a technical degree centred around game engineering/technologies with transferable skills, problem solving, mathematics, software engineering,scalability, and industry practices.
openaire +1 more source
EKSPLORASI TEKNIK GAMEPLAY DAN GAME MECHANICS RANCANGAN CARLO FABRICATORE PADA GAME DOTA 2 [PDF]
, 2015 Didalam sebuah game terdapt gameplay dan game mechanics. Dua unsur ini sudah menjadi bagian yang terpenting dalam desain sebuah game. Gameplay merupakan kegiatan yang sering dilakukan ketika memainkan sebuah game sedangkan game mechanics merupakan alat
Agung Satrio Ardi, Alumni +2 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
External sources of clean technology: evidence from the clean development mechanism [PDF]
, 2013 New technology is fundamental to sustainable development. However, inventors from industrialized countries often refuse technology transfer because they worry about reverse-engineering. When can clean technology transfer succeed?
A Dechezleprêtre +33 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Game TicTacToe Dengan Gerakan Jari Menggunakan Metode Viola And Jones [PDF]
, 2011 Perkembangan dunia Game komputer telah mengalami kemajuan yang amat pesat. Sehingga para developer Game komputer terus mengembangkan Game yang user friendly atau mudah digunakan oleh semua orang dengan desain grafik user interface yang menarik dan ...
Nugraha, Raditya +2 more
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