Results 241 to 250 of about 174,191 (305)

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

open access: yesAdvanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob   +12 more
wiley   +1 more source

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu   +11 more
wiley   +1 more source

Two-Dimensional Dynamic Logic Resource Allocation for Scalable RIS Channel Emulation. [PDF]

open access: yesSensors (Basel)
Fei D   +9 more
europepmc   +1 more source

Game Engine Architecture and Comparative Study of Different Game Engines

2021 12th International Conference on Computing Communication and Networking Technologies (ICCCNT), 2021
Nowadays Game Engines have become an integral component of the game development environment. Not only do they accelerate the game development process but also facilitate the integration of gaming modules like animations, graphics, artificial intelligence, and physics using their in-built functionalities.
Chaitya Vohera   +4 more
openaire   +1 more source

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