Results 41 to 50 of about 530,636 (313)

Some Anthropometric Measurements and Sensor motor Perceptions and their Relation to Performance Level of Individual Play for Speedball Players [PDF]

open access: yesAssiut Journal of Sport Science and Arts, 2017
This research aims to: 1- Identify the relationship between some (A.M) () and the level of performance of the individual play of speedball players. 2- Identify the relationship between some of (S.M.P) and the performance level of the individual play ...
Mohamed El-Shinawy
doaj   +3 more sources

IMU-Based Fitness Activity Recognition Using CNNs for Time Series Classification

open access: yesSensors
Mobile fitness applications provide the opportunity to show users real-time feedback on their current fitness activity. For such applications, it is essential to accurately track the user’s current fitness activity using available mobile sensors, such as
Philipp Niklas Müller   +3 more
doaj   +1 more source

Acknowledgement to Reviewers of Games in 2014

open access: yesGames, 2015
The editors of Games would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2014:[...]
Games Editorial Office
doaj   +1 more source

Pornographic Games on Steam : Genres, Modes, and Milieus

open access: yes, 2023
Pornographic games have historically been distributed outside of mainstream channels. Steam, in 2018, change its policy allowing uncensored pornographic games to be sold.
Lankoski, Petri, Välisalo, Tanja
core  

Games outside of games [PDF]

open access: yes, 2022
The games industry is highly competative and the skills needed to be successful can also be used in other sectors. This talk explored transferable skills and the link between the games industry and a whole range of future careers that are XR related and ...
Ward, G.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A Classification of Scripting Systems for Entertainment and Serious Computer Games

open access: yes, 2011
The technology base for modern computer games is usually provided by a game engine. Many game engines have built-in dedicated scripting languages that allow the development of complete games that are built using those engines, as well as extensive ...
Anderson, Eike F., Eike Falk Anderson
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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