Results 51 to 60 of about 159,978 (265)
Levels for Hotline Miami 2: Wrong Number Using Procedural Content Generations
Computers, 2018 Procedural Content Generation is the automatic process for generating game content in order to allow for a decrease in developer resources while adding to the replayability of a digital game.
Joseph Alexander Brown +3 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Playing Games with Timed Games [PDF]
IFAC Proceedings Volumes, 2009 In this paper we focus on property-preserving preorders between timed game automata and their application to control of partially observable systems. Following the example of timed simulation between timed automata, we define timed alternating simulation as a preorder between timed game automata, which preserves controllability.
Chatain, Thomas +2 more
openaire +3 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Acknowledgement to Reviewers of Games in 2015
Games, 2016 The editors of Games would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. [...]
Games Editorial Office
doaj +1 more source
Game—The Dressing Change Game [PDF]
INFORMS Transactions on Education, 2015 Many employees face operational failures—missing or insufficient supplies, equipment, information, and personnel—that interfere with their workflow and can negatively impact organizational performance. However, employees often devise methods to work around these obstacles that may come with negative side effects.
Anita L. Tucker, Cindy Lefton
openaire +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Acknowledgement to Reviewers of Games in 2013
Games, 2014 The editors of Games would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2013.
Games Editorial Office
doaj +1 more source
Educational units by using the new tools and music to improve the Motor abilities of autism children [PDF]
International Journal of Sports Science and Arts, 2016 Aim of the research: Building units educational tools developed using the motor and musician, and get to know their impact in improving motor developmental capacity of children with autism (Phase I).
Ranya Hassan, Mahmoud Mahmoud
doaj +1 more source