Results 51 to 60 of about 791,132 (305)

Minkowski Games [PDF]

open access: yesACM Transactions on Computational Logic, 2018
We introduce and study Minkowski games. These are two-player games, where the players take turns to choose positions in R<sup<d</sup< based on some rules. Variants include boundedness games, where one player wants to keep the positions bounded, and the other wants to escape to infinity; as well as safety games, where one player wants to ...
Stéphane Le Roux 0001   +2 more
openaire   +10 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Pornographic Games on Steam : Genres, Modes, and Milieus

open access: yes, 2023
Pornographic games have historically been distributed outside of mainstream channels. Steam, in 2018, change its policy allowing uncensored pornographic games to be sold.
Lankoski, Petri, Välisalo, Tanja
core   +1 more source

PEMBERDAYAAN USAHA KECIL BERBASIS POTENSI EKONOMI NAGARI SUNGAI KAMUYANG

open access: yesWarta Pengabdian Andalas, 2018
The objective of this community service program is to enhance undertanding about the economic empowerment in Nagari Sungai Kamuyang. This is based on the nagari and regional economic potential.
Donard Games
doaj  

Levels for Hotline Miami 2: Wrong Number Using Procedural Content Generations

open access: yesComputers, 2018
Procedural Content Generation is the automatic process for generating game content in order to allow for a decrease in developer resources while adding to the replayability of a digital game.
Joseph Alexander Brown   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Playing Games with Timed Games [PDF]

open access: yesIFAC Proceedings Volumes, 2009
In this paper we focus on property-preserving preorders between timed game automata and their application to control of partially observable systems. Following the example of timed simulation between timed automata, we define timed alternating simulation as a preorder between timed game automata, which preserves controllability.
Chatain, Thomas   +2 more
openaire   +3 more sources

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Game—The Dressing Change Game [PDF]

open access: yesINFORMS Transactions on Education, 2015
Many employees face operational failures—missing or insufficient supplies, equipment, information, and personnel—that interfere with their workflow and can negatively impact organizational performance. However, employees often devise methods to work around these obstacles that may come with negative side effects.
Anita L. Tucker, Cindy Lefton
openaire   +1 more source

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