Results 51 to 60 of about 548,170 (292)
Journal of Theoretical Biology, 2013 The basic idea of evolutionary game theory is that payoff determines reproductive rate. Successful individuals have a higher payoff and produce more offspring. But in evolutionary and ecological situations there is not only reproductive rate but also carrying capacity. Individuals may differ in their exposure to density limiting effects.
Sebastian Novak +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Juego, videojuego y creación de sentido. Una introducción
Comunicación, 2022 El objetivo de este artículo es servir de introducción al estudio de la creación de sentido a través del acto de jugar con juegos, juguetes y videojuegos.
Gonzalo Frasca
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Tópicos y arquetipos de la opinión pública: la construcción social de la enfermera
Enfermería Global, 2011 La indagación realizada intenta mostrar el sufrimiento y menosprecio de las mujeres en un trayecto de la historia. Concateno el ser mujer y su relación con la disciplina enfermera, por ser la enfermería desde sus ancestros, una actividad netamente ...
María Inés Games
doaj +1 more source
Rules, Games, and Common-Pool Resources
, 1994 While the tragedy of the commons is real, there are many instances where institutions develop to protect against overexploitation. In this important work, the authors explore empirically, theoretically, and experimentally the nature of such institutions ...
E. Ostrom, R. Gardner, James M. Walker
semanticscholar +1 more source
Evolutionary games on graphs [PDF]
, 2006 Game theory is one of the key paradigms behind many scientific disciplines from biology to behavioral sciences to economics. In its evolutionary form and especially when the interacting agents are linked in a specific social network the underlying ...
G. Szabó, G. Fáth
semanticscholar +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Sensors, 2023 A brain–computer interface (BCI) is a computer-based system that allows for communication between the brain and the outer world, enabling users to interact with computers using neural activity. This brain signal is obtained from electroencephalogram (EEG)
Radia Rayan Chowdhury +2 more
doaj +1 more source