Plasmodium falciparum gametocytes: their longevity and infectivity
The longevity and infectivity of isolated populations of Plasmodium falciparum gametocytes were studied. Following chloroquine treatment gametocyte numbers fell with a constant rate of loss over a period of 16–24days; the populations had a half-life of 2·4 days. The sex ratio stayed constant throughout at 4 female:1 male.
M E, Smalley, R E, Sinden
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A chemical susceptibility profile of thePlasmodium falciparumtransmission stages by complementary cell-based gametocyte assays [PDF]
Sarah D’Alessandro +10 more
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Gametocytes, sporozoites and liver schizonts.
Plasmodium falciparum differs from other human species of Plasmodium in the short, limited exo-erythrocytic stage in the life cycle, which is an apparent disadvantage in surviving through a prolonged non-transmission season such as occurs throughout much of tropical Africa.
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Genotyping Plasmodium falciparum gametocytes using amplicon deep sequencing
Background Understanding the dynamics of gametocyte production in polyclonal Plasmodium falciparum infections requires a genotyping method that detects distinct gametocyte clones and estimates their relative frequencies. Here, a marker was identified and
Jimmy Vareta +7 more
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A review of the effects of artemether-lumefantrine on gametocyte carriage and disease transmission [PDF]
Michael Makanga
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Can field-based mosquito feeding assays be used for evaluating transmission-blocking interventions?
A recent meta-analysis of mosquito feeding assays to determine the Plasmodium falciparum transmission potential of naturally infected gametocyte carriers highlighted considerable variation in transmission efficiency between assay methodologies and ...
Bousema, Teun +3 more
core +4 more sources
A male gametocyte osmiophilic body and microgamete surface protein of the rodent malaria parasitePlasmodium yoelii(PyMiGS) plays a critical role in male osmiophilic body formation and exflagellation [PDF]
Mayumi Tachibana +4 more
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Combination therapy that includes artemisinin derivatives cures most falciparum malaria infections. Lowering transmission by reducing gametocyte infectivity would be an additional benefit.
Targett, G +10 more
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Gametocytes infectiousness to mosquitoes: variable selection using random forests, and zero inflated models [PDF]
Malaria control strategies aiming at reducing disease transmission intensity may impact both oocyst intensity and infection prevalence in the mosquito vector.
Genuer, Robin +2 more
core +3 more sources
AGE-DEPENDENT DISTRIBUTION OF PLASMODIUM FALCIPARUM GAMETOCYTES QUANTIFIED BY PFS25 REAL-TIME QT-NASBA IN A CROSS-SECTIONAL STUDY IN BURKINA FASO [PDF]
Abdoul-Rahim Ouédraogo +6 more
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