Results 171 to 180 of about 9,642 (218)

Comparing the transmission blocking efficacy of Primaquine and Tafenoquine with in vivo pre-clinical models

open access: yes
Duffey M   +9 more
europepmc   +1 more source

Plasmodium falciparum: Generation of pure gametocyte culture by heparin treatment [PDF]

open access: yesExperimental Parasitology, 2013
In vitro culture of Plasmodium falciparum gametocytes is essential for studying sexual development of the parasite. Here we describe a simple method for producing synchronous gametocyte culture without contamination of asexual stages. This method employs
Daniel M Parker   +2 more
exaly   +2 more sources

Gametocyte-Forming and Non-Gametocyte-Forming Clones of Plasmodium Falciparum

The American Journal of Tropical Medicine and Hygiene, 1984
Three clones have been prepared from the Honduras I/CDC strain of Plasmodium falciparum by a method of microscopic selection. One of these (HB-2) does not form gametocytes whereas the others (HB-1 and HB-3) do. All three are as resistant to pyrimethamine as the original line, and all three form knobs on the erythrocyte surface.
V K, Bhasin, W, Trager
openaire   +2 more sources

Gametocytes and Gametes

2014
Gametes and their precursors, the gametocytes, are the very special cell types that Plasmodium developed in the course of evolution to accomplish such key steps in its life cycle and are the subject of this chapter. In the main, cellular and molecular aspects of gametocyte and gamete formation will be covered here.
Pietro Alano, Oliver Billker
openaire   +1 more source

Gametogenesis in culture by gametocytes of Plasmodium falciparum

Nature, 1977
CONTINUOUS culture of human malaria parasites, Plasmodium falciparum, in human red blood cells was first reported by Trager and Jensen1 and subsequently by Haynes and co-workers2. The culture system described by Trager and Jensen supports the asexual multiplication of P.
R, Carter, R F, Beach
openaire   +2 more sources

The Fine Structure of the Gametocytes of an Adeleine Haemogregarine

The Journal of Protozoology, 1967
SYNOPSIS. Gametocytes of an unidentified haemogregarine (Sporozoa, Telosporea, Coccidia, Eucoccida, Adeleina, Haemogregarinicae) from the frog Rana montezumae were examined by light and electron microscopy. The fully‐grown gametocytes lay in a vacuole in the erythrocyte, surrounded by a sheath which was probably of parasitic origin.
J R, Baker, R, Lainson
openaire   +2 more sources

A Loss of Gametocytes in Plasmodium elongatum

The Journal of Parasitology, 1947
The following study grew out of work on the susceptibility of various species of mosquitoes to the avian malarial parasite, Plasmodium elongatum, and its transmission through the mosquito to the canary and the duck. A review of the literature revealed the following references to the sexual forms. P. elongatum was named after its gametocyte (Huff, 1930)
openaire   +2 more sources

The Optimal Production of Gametocytes byPlasmodium falciparum

Journal of Theoretical Biology, 1998
We use a simple model of the blood-stage infection dynamics of the malaria parasite Plasmodium falciparum to consider the adaptive significance of different rates of conversion from its pathogenic, asexual stages to its transmissible, sexual forms. We find that maximize transmissivity in single-strain infections are generally greater than the highest ...
F E, McKenzie, W H, Bossert
openaire   +2 more sources

Observations on the infectiousness of gametocytes in hyperendemic malaria

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1953
Abstract 1. (1) There is a correlation between the probability of a mosquito's becoming infected and the gametocyte density of the carrier, when densities are broadly grouped. 2. (2) A small series of experiments in the hyperendemic zone of S. W. Nigeria are reported in which A.
openaire   +2 more sources

Gene expression in Plasmodium: from gametocytes to sporozoites

International Journal for Parasitology, 2004
Completion of the complex developmental program of Plasmodium in the mosquito is essential for parasite transmission, yet this part of its life cycle is still poorly understood. In recent years, considerable progress has been made in the identification and characterization of genes expressed during parasite development in the mosquito.
C K, Moreira   +2 more
openaire   +2 more sources

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