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Erythrocyte Membrane Makeover by Plasmodium falciparum Gametocytes [PDF]
Frontiers in Microbiology, 2019 Plasmodium falciparum sexual parasites, called gametocytes, are the only parasite stages responsible for transmission from humans to Anopheles mosquitoes. During their maturation, P. falciparum gametocytes remodel the structural and mechanical properties
Gaëlle Neveu +3 more
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Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence "transmission blocking" assay. [PDF]
PLoS ONE, 2012 BACKGROUND: Current anti-malarial drugs have been selected on the basis of their activity against the symptom-causing asexual blood stage of the parasite.
Joël Lelièvre +6 more
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Viability and Infectivity of Plasmodium vivax Gametocytes in Short-Term Culture
Frontiers in Cellular and Infection Microbiology, 2021 The control and elimination of malaria caused by Plasmodium vivax both represent a great challenge due to the biological aspects of the species. Gametocytes are the forms responsible for the transmission of the parasite to the vector and the search for ...
Glenda Quaresma Ramos +12 more
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An atlas of novel microtubule-associated proteins in the malaria parasite Plasmodium falciparum [PDF]
mBioMature gametocytes of Plasmodium falciparum exhibit a characteristic falciform shape, which is conferred by a complex array of subpellicular microtubules (SPMTs) associated with the inner membrane complex (IMC).
Korbinian Niedermüller +13 more
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P. falciparum PEBP protein is dispensable during asexual and sexual stages of development [PDF]
Frontiers in Cellular and Infection MicrobiologyMalaria, a life-threatening disease caused by protozoan parasite Plasmodium and transmitted by mosquitoes, remains a significant threat to health worldwide, especially in the face of emerging drug resistance.
Baishali Chakraborty +3 more
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Plasmodium falciparum PP1 phosphatase is a key regulator of malaria parasite transmission [PDF]
mBioFor the successful transmission of malaria parasites from humans to mosquitoes, Plasmodium falciparum gametocytes must remain in the bloodstream long enough to be taken up by a mosquito. Once ingested, they are then activated into gametes to continue the
Ludivine Royer +10 more
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Frontiers in Cellular and Infection Microbiology, 2018 The gametocytes of Plasmodium falciparum, responsible for the transmission of this malaria parasite from humans to mosquitoes, accumulate and mature preferentially in the human bone marrow. In the 10 day long sexual development of P.
Valeria Messina +8 more
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Frontiers in Cellular and Infection Microbiology, 2022 The unique biological features of Plasmodium vivax not only make it difficult to control but also to eliminate. For the transmission of the malaria parasite from infected human to the vector, gametocytes play a major role. The transmission potential of a
Anthony Ford +12 more
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Microbiology Spectrum, 2023 Our overall understanding of the developmental biology of malaria parasites has been greatly enhanced by recent advances in transcriptomic analysis. However, most of these investigations rely on laboratory strains (LS) that were adapted into in vitro ...
Jonas A. Kengne-Ouafo +12 more
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Plasmodium vivax Gametocytes Adherence to Bone Marrow Endothelial Cells
Frontiers in Cellular and Infection Microbiology, 2021 In a Plasmodium vivax infection, it was shown a proportionally increased on gametocyte distribution within the bone marrow aspirant, suggesting a role of this organ as a reservoir for this parasite stage.
Luis Carlos Salazar Alvarez +17 more
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