Results 11 to 20 of about 803 (130)
Antibody Responses to Crude Gametocyte Extract Predict Plasmodium falciparum Gametocyte Carriage in Kenya [PDF]
Frontiers in Immunology, 2021 BackgroundMalaria caused by Plasmodium falciparum remains a serious global public health challenge especially in Africa. Interventions that aim to reduce malaria transmission by targeting the gametocyte reservoir are key to malaria elimination and/or eradication. However, factors that are associated with gametocyte carriage have not been fully explored.
Brian R. Omondi +13 more
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The Coming-Out of Malaria Gametocytes [PDF]
Journal of Biomedicine and Biotechnology, 2010 The tropical disease malaria, which results in more than one million deaths annually, is caused by protozoan parasites of the genusPlasmodiumand transmitted by blood-feeding Anopheline mosquitoes. Parasite transition from the human host to the mosquito vector is mediated by gametocytes, sexual stages that are formed in human erythrocytes, which ...
Kuehn, Andrea, Pradel, Gabriele
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Plasmodium vivax gametocytes and transmission
Parasitology International, 2022 Malaria elimination means cessation of parasite transmission. At present, the declining malaria incidence in many countries has made elimination a feasible goal. Transmission control has thus been placed at the center of the national malaria control programs.
Sirasate, Bantuchai +2 more
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Frontiers in Cellular and Infection Microbiology, 2023 IntroductionRecent evidence suggests that the bone marrow (BM) plays a key role in the diffusion of P. falciparum malaria by providing a “niche” for the maturation of the parasite gametocytes, responsible for human-to-mosquito transmission.
Samantha Donsante +11 more
doaj +1 more source
Cell Reports, 2019 Summary: Plasmodium falciparum gametocytes infect mosquitoes and are responsible for malaria transmission. New interventions that block transmission could accelerate malaria elimination. Gametocytes develop within erythrocytes and activate protein export
Charlie Jennison +8 more
doaj +1 more source
mSphere, 2020 We developed a flow-cytometry-based method to separate and collect cocultured male and female Plasmodium falciparum gametocytes responsible for malaria transmission. The purity of the collected cells was estimated at >97% using flow cytometry, and sorted
Melanie C. Ridgway +3 more
doaj +1 more source
mSphere, 2018 Sexual reproduction is an obligate step in the Plasmodium falciparum life cycle, with mature gametocytes being the only form of the parasite capable of human-to-mosquito transmission.
Katelyn A. Walzer +3 more
doaj +1 more source
Malaria Journal, 2012 Background Plasmodium falciparum immature gametocytes accumulate in the bone marrow, but their exact location in this tissue remains unclear. Methods The stage and deposition pattern of gametocytes was analysed on histological sections of a bone marrow ...
Farfour Eric +4 more
doaj +1 more source
Phagocytosis and activation of bone marrow‐derived macrophages by Plasmodium falciparum gametocytes
Malaria Journal, 2021 Background The innate immune response against various life cycle stages of the malaria parasite plays an important role in protection against the disease and regulation of its severity.
Yolanda Corbett +10 more
doaj +1 more source
HIV-1 Impact on Malaria Transmission: A Complex and Relevant Global Health Concern
Frontiers in Cellular and Infection Microbiology, 2021 Malaria/HIV-1 co-infection has become a significant public health problem in the tropics where there is geographical overlap of the two diseases. It is well described that co-infection impacts clinical progression of both diseases; however, less is known
Ashleigh Roberds +3 more
doaj +1 more source