Results 261 to 270 of about 94,242 (328)

Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models of epilepsy. We studied potential ECM changes in a mouse model of pilocarpine‐induced status epilepticus (PISE) and their potential contributions to
AnnaLin M. Woo, Erik J. Fleischel, Dipan C. Patel, Harald Sontheimer   +3 more
wiley   +1 more source

Gamma-aminobutyric acid interactions with phytohormones and its role in modulating abiotic and biotic stress in plants. [PDF]

Stress Biol
Islam SNU, Kouser S, Hassan P, Asgher M, Shah AA, Khan NA.   +5 more
europepmc   +1 more source

Intersection of epilepsy and cardiac health: Insights from electrocardiography and syndromic associations

Epilepsia, EarlyView.
Abstract Epilepsy is a chronic neurological condition marked by recurrent, uncontrolled seizures. Identifying comorbidities in epilepsy is critical for preventing mortality. Among these, the autonomic nervous system's role in epilepsy often manifests as cardiac disorders. Patients with epilepsy (PWE), particularly those with poorly controlled seizures,
Enes Akyuz, Feyza Sule Aslan, Tugba Eyigurbuz   +2 more
wiley   +1 more source

Integrated Metabolomic and Transcriptomic Analysis Reveals the Molecular Regulatory Mechanism of Gamma-Aminobutyric Acid Accumulation in White Quinoa (<i>Chenopodium quinoa</i> Willd.) in Response to Dark and Ultrasound Stress. [PDF]

Foods
Wu M, Zhou Q, Sun Y, Zhou L, Li D, Ren T, Zheng Y, Zhao W, Wang J.   +8 more
europepmc   +1 more source

GABRA2‐related encephalopathy: Identification of two phenotypes with distinctive electroclinical features

Epilepsia, EarlyView.
Abstract Pathogenic variants in γ‐aminobutyric acid type A (GABAA) receptor subunit genes are increasingly associated with epilepsy and neurodevelopmental disorders. Pathogenic variants in GABRA2, encoding the α‐2 subunit of GABAA receptors, have been recently reported.
Marie Adamo‐Croux, Chloé Angelini, Jérôme Aupy, Laurent Villard, Nathalie Villeneuve, Arnaud Chefdor, Yorsa Halleb, Maxime Colmard, Manon Degoutin, Gaetan Lesca, Perrine Charles, Boris Keren, Nicole Chemaly, Cyril Goizet, Mathieu Milh, Claire Bar   +15 more
wiley   +1 more source

GABA (gamma-aminobutyric acid) levels in dorsal anterior cingulate cortex are negatively associated with food motivation in a pediatric sample. [PDF]

Sci Rep
Duck SA, Smith KR, Saleh MG, Jansen E, Papantoni A, Song Y, Edden RAE, Carnell S.   +7 more
europepmc   +1 more source

Striatal glutamic acid and .GAMMA.-aminobutyric acid in transient cerebral ischemia in spontaneously hypertensive rats.

, 1990
Hiroshi Yao, Takashi Matsumoto, Makoto Hirano, Hideyuki Uchimura, Hiroaki Ooboshi, Seizo Sadoshima, Masatoshi Fujishima   +6 more
openalex   +2 more sources

Neuronal oscillatory imbalances in GNAO1‐related disorders associated with disease severity

Epilepsia, EarlyView.
Abstract Objective This study investigates excitatory/inhibitory (E/I) imbalances in GNAO1‐related disorders (GNAO1‐RD), linking neuronal dysfunction to clinical severity using E/I‐sensitive electroencephalography (EEG) analyses. Methods We conducted an observational study involving 12 children with GNAO1‐RD caused by pathogenic variants and 36 age ...
Tongyu Wang, Jana Domínguez‐Carral, William Grant Ludlam, Mar Junyent Segarra, Montserrat Fornaguera Marti, Hilgo Bruining, Kirill A. Martemyanov, Klaus Linkenkaer‐Hansen, Juan Dario Ortigoza‐Escobar   +8 more
wiley   +1 more source

Cannabidiol attenuates epileptic phenotype and increases survival in a mouse model of developmental and epileptic encephalopathy type 1

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathy type 1 (DEE1) is a rare drug‐resistant pediatric epilepsy caused by trinucleotide repeat expansions in the X‐linked ARX gene, leading to elongation of the first polyalanine tract. It presents with early onset tonic seizures or spasms, developmental and cognition delay, and high risk of ...
Lucia Verrillo, Fabio Arturo Iannotti, Denise Drongitis, Katiuscia Martinello, Loredana Poeta, Adriano Barra, Gaetano Terrone, Sergio Fucile, Vincenzo Di Marzo, Maria Giuseppina Miano   +9 more
wiley   +1 more source

Optimisation of fermentation conditions for the production of gamma-aminobutyric acid (GABA)-rich soy sauce. [PDF]

Heliyon
Shin Yee C, Ilham Z, Cheng A, Abd Rahim MH, Hajar-Azhari S, Yuswan MH, Mohd Zaini NA, Reale A, Di Renzo T, Wan-Mohtar WAAQI.   +9 more
europepmc   +1 more source