Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi +4 more
wiley +1 more source
Gamma-Aminobutyric Acid (GABA) as a Defense Booster for Wheat against Leaf Rust Pathogen (Puccinia triticina). [PDF]
Khalil HB +9 more
europepmc +1 more source
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley +1 more source
Is there an association between cognitive impairment and urinary adrenaline, norepinephrine, gamma-aminobutyric acid, and taurine levels in children with obstructive sleep apnea?: A case control study. [PDF]
Ji J, Wang Y, Chen B, Xu X, Lv M.
europepmc +1 more source
Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley +1 more source
Anti-Gamma Aminobutyric Acid B (GABA B) Antibody Receptor-Associated Autoimmune Encephalitis in Pregnancy: A Rare Condition. [PDF]
Mazumdar MA, Bansal S, Shukla I.
europepmc +1 more source
Narcolepsy and rapid eye movement sleep
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini +4 more
wiley +1 more source
Enhanced inhibitory effects of gamma-aminobutyric acid on renal and hepatic function, molecular profiles, and histological changes in male albino mice. [PDF]
Ajeel MA, Al-Robaiee IA.
europepmc +1 more source
Gut microbiota-derived gamma-aminobutyric acid improves host appetite by inhibiting satiety hormone secretion. [PDF]
Li S +9 more
europepmc +1 more source
Gamma-aminobutyric acid interactions with phytohormones and its role in modulating abiotic and biotic stress in plants. [PDF]
Islam SNU +5 more
europepmc +1 more source

