Results 321 to 330 of about 93,041 (352)

Immunostimulating property of gamma-aminobutyric acid

Bulletin of Experimental Biology and Medicine, 1987
The writers previously [2, 3] showed that 9 of the 20 amino acids present in the composition of proteins (Asp, Asn, Glu, Cys, Set, Thr, Trp, Ala, Val) can induce Thy-I-antigen on bone marrow cells and can stimulate the sinus-dependent immune response in mice.
G. A. Belokrylov, I. V. Molchanova
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Gamma-Aminobutyric Acid as a Neurotrophic Agent [PDF]

, 1988
There is accumulating evidence that different classical neurotransmitters such as serotonin, catecholamines and the amino acid GABA may serve as epigenetic factors during neuronal development and differentiation (1, 2, 3, 4). Since a variety of macromolecular compounds, mainly peptides, are also known to act as neurotrophic factors (5) it is clear that
R. Hammerschlag, Bo Belhage, E. Meier, Arne Schousboe, Gert H. Hansen   +4 more
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The determination of gamma-aminobutyric acid in brain

Analytical Biochemistry, 1962
Abstract A simple method for the determination of γ-aminobutyric acid in brain tissue is described. Two columns of ion-exchange resin are used. An extract of rat brain is first passed through Amberlite CG-50, which removes basic amino acids and amines.
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IONS AND THE TRANSPORT OF GAMMA‐AMINOBUTYRIC ACID BY SYNAPTOSOMES

Journal of Neurochemistry, 1972
Abstract— The initial rate of uptake of [2,3‐3H]gamma‐aminobutyric acid by rat brain synaptosomes was studied under incubation conditions in which GABA metabolism was minimal. The presence of both sodium and potassium in the incubation medium was essential for sustained uptake. Uptake proceeded for a short period of time in the absence of potassium and
A. A. Smith, David L. Martin
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Inhibition of a gamma aminobutyric acid A receptor by caffeine

NeuroReport, 1994
The effect of caffeine was studied on the progress of gamma aminobutyric acid A receptor channel (GABAAR) mediated transmembrane 36Cl-flux and [3H]GABA release in native membrane vesicles from rat cerebral cortex using rapid kinetic techniques. GABA response on the second time-scale mediated by the slower desensitizing GABAAR was inactivated by 5 mM ...
Tamás Blandl, Julianna Kardos
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Measurement of gamma-aminobutyric acid (GABA) in blood

Life Sciences, 1978
Abstract Blood GABA levels can be readily determined using a radioreceptor assay or gas chromatography-mass spectrometry. After withdrawal of blood, GABA levels remain stable with 25–50% of the GABA in whole blood found in the plasma fraction. Whole blood GABA concentrations range from 500 pmoles/ml to 1200 pmoles/ml in 8 mammalian species with human
S.J. Enna, William E. Seifert, L.A. Smith, Richard M. Caprioli, John W. Ferkany   +4 more
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Gamma-Aminobutyric Acid (GABA)

2000
In the last decades there has been a rapid increase in interest in the study of the central amino acid neurotransmitters, especially in the role of γ-aminobutyric acid (GABA) in certain neurological and psychiatric problems.
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Antiseizure activity of gamma-acetylenic gamma-aminobutyric acid: a catalytic irreversible inhibitor of gamma-aminobutyric acid transaminase.

The Journal of Pharmacology and Experimental Therapeutics, 1977
gamma-Acetylenic gamma-aminobutyric acid (gamma-acetylenic GABA) produces several-fold sustained elevations of brain GABA concentrations when administered intraperitoneally to mice. It protects mice against seizures induced by audiogenic stimuli, electroshock, thiosemicarbazide, isoniazid and strychnine.
Schechter, P J, Tranier, Y, Jung, M J, Sjoerdsma, A   +3 more
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Convulsants and Gamma-Aminobutyric Acid Receptors

1994
Gamma-aminobutyric acid (GABA) is the major inhibitory transmitter of the mammalian CNS and has been implicated in the aetiology of a number of clinically important disorders (Bartholini et al. 1985), including epilepsy (Gale 1989). The complexity of neuronal integration in the brain has precluded any detailed understanding of these conditions, though ...
I. L. Martin, S. C. R. Lummis
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GAMMA-AMINOBUTYRIC-ACID ANALOGUES

The Lancet, 1978
G. Bartholini, J.-P. Kaplan, K.G. Lloyd
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