Results 91 to 100 of about 511,926 (249)

Intersection of systemic lupus erythematosus and autoimmune thyroid disease: Shared pathophysiology, epidemiology, diagnosis, and management

Rheumatology &Autoimmunity, EarlyView.
A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa, Awalia Awalia, Deasy Ardiany, Henry Sutanto   +3 more
wiley   +1 more source

Role of Non-Thermal Processing Technologies in Modulating Protein Allergenicity in Legumes. [PDF]

Food Sci Nutr
Non‐thermal processing technologies (NTTs) reduce legumes' allergenicity while preserving quality and nutrients retention (PEF, pulsed electric field; CP, cold plasma; HPP, high pressure processing; US, ultrasound; IR, infrared). ABSTRACT The global shift toward plant‐based diets has increased legume consumption due to health and environmental benefits.
Ngabonzima V, Ekezie FGC, Aryee ANA, Onuh JO.   +3 more
europepmc   +2 more sources

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

Small, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo, Serena Renzi, Martina B. Violatto, Leila Altigieri, Anna L. Capriotti, Andrea Cerrato, Aldo Laganà, Luca Digiacomo, Erica Quagliarini, Antonio Minopoli, Massimiliano Papi, Daniela Pozzi, Carlo A. Scirè, Pietro Invernizzi, Paolo Bigini, Giulio Caracciolo   +15 more
wiley   +1 more source

Co-immunoprecipitation based isolation and identification of Interacting Phytal and Rheumatoid arthritis subject’s serum globulins proteins

Journal of BioScience and Biotechnology
Phytalproteins have an immense role in plant’s growth and sustenance processes. They can be used as nutritional enhancers of foods we consume. Rheumatoid arthritis is an autoimmune disorder, prevalent in both sexes of humans and especially those above ...
Jayaparada Rao Chunduri, Pragati Bhatt, Rupal H Desai   +2 more
doaj   +1 more source

Oxidative Damage, Energy Imbalance, and Behavioral Disruptions in Girardia tigrina Exposed to Treated Sewage Effluents

Environmental Toxicology, EarlyView.
ABSTRACT This study assessed the ecotoxicological effects of treated sewage on the freshwater planarian Girardia tigrina, integrating biochemical, energetic, and behavioral biomarkers. Planarians were exposed for 48 h to different concentrations of treated sewage (12.5%, 25%, 50%, and 100%) and compared to controls using commercial water and water from
Renata M. P. Freitas, Pedro H. Carvalho, Daniela de Melo e Silva, Carlos Gravato   +3 more
wiley   +1 more source

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source

The Bidirectional Association Between MASLD and Male Hypogonadism: An Updated Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) and male hypogonadism are increasingly prevalent, metabolically interrelated conditions. Testosterone (T) deficiency has been implicated in hepatic lipid dysregulation, insulin resistance, and visceral adiposity, whereas MASLD may impair the hypothalamic–pituitary ...
Giorgia Spaggiari, Leonardo Dalla Valentina, Cristina Felicani, Filippo Gabrielli, Simonetta Lugari, Giovanni Corona, Paolo Ventura, Manuela Simoni, Fabio Nascimbeni, Daniele Santi   +9 more
wiley   +1 more source

Growth and Blood Parameters of Weaned Crossbred Beef Calves Fed Forage Kale (Brassica oleracea spp. acephala)

Advances in Agriculture, 2015
Forty lightweight calves (206.4±3.2 kg) were randomly distributed to four treatments: (Control) low nutritive value pasture and hay plus 1 kg d−1 of rolled barley; (Pasture) management intensive pasture; (Haylage) timothy haylage; and (Kale) 50% timothy ...
Y. Chorfi, Y. Couture, G. F. Tremblay, R. Berthiaume, D. Cinq-Mars   +4 more
doaj   +1 more source

Serum hepatic biochemistry and electrophoretic protein profile of healthy and Ehrlich tumor-bearing mice treated with extracts of Agaricus blazei Murill

Semina: Ciências Agrárias, 2016
Compounds isolated from Agaricus blazei Murill represent a group of promising natural immunomodulators for use in the treatment of neoplasms. We have evaluated the serum biochemical profile of healthy and Ehrlich tumor-bearing mice treated with different
Durval Verçosa Junior, Neide Judith Faria de Oliveira, Eduardo Robson Duarte, Gabriela Almeida Bastos, Ana Cláudia Maia Soares, Geovanni Dantas Cassali, Benito Soto-Blanco, Marília Martins Melo   +7 more
doaj   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source