Results 51 to 60 of about 16,806 (319)

A Novel Therapeutic Strategy for Bone Marrow Failure: Niche Rejuvenation Using Costal Cartilage‐Derived Stem Cells

open access: yesAdvanced Science, EarlyView.
CDSCs exhibit the potential to differentiate into endothelial cells, vascular pericytes, and osteoblasts. These differentiated cells are capable of secreting additional pro‐hematopoietic cytokines. Furthermore, CDSCs can inhibit apoptosis and reduce DNA damage in injured hematopoietic stem and progenitor cells (HSPCs, including RHSCs and RHPCs), while ...
Rui Dong   +16 more
wiley   +1 more source

GLM7 – A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity

open access: yesAdvanced Science, EarlyView.
This study leverages NHANES data to analyze 49 routine indicators, identifying the top 10 diagnostic markers for five major diseases and introducing GLM7, a novel indicator. Restricted cubic spline analyses, forest plot evaluations, and XGBoost modeling demonstrate conventional indicators' efficacy and GLM7's value for disease diagnosis/prediction ...
Zhihua Wang   +8 more
wiley   +1 more source

Isolation and characterization of a light chain variable region gene for human rheumatoid factors. [PDF]

open access: yes, 1987
Previously, we isolated a Vk gene (Humkv325) from a human placenta that encodes RF light chains bearing the PSL2 and PSL3 CRI markers. Here we report the isolation and characterization of a second human Vk gene (Humkv328) that can be used for RF ...
Carson, DA   +4 more
core  

Enhanced Multitask Learning with Attention Sparse Routing Mechanism for Intelligent Diabetes Prediction

open access: yesAdvanced Intelligent Systems, EarlyView.
The model leverages patient time‐space information for pattern feature representations. Encoders extract first and second‐order features, aggregated with categorical embeddings and dense features. Task‐specific and shared experts use gated networks, with a dispatch layer routing information for diabetes risk evaluation and blood glucose prediction ...
Yingshuai Wang   +8 more
wiley   +1 more source

Serum Biochemical Phenotypes in the Domestic Dog [PDF]

open access: yes, 2016
The serum or plasma biochemical profile is essential in the diagnosis and monitoring of systemic disease in veterinary medicine, but current reference intervals typically take no account of breed-specific differences.
Chang, Y M   +3 more
core   +8 more sources

Biochemical screening of Hisex brown cross chickens after multiple vaccinations

open access: yesUkrainian Journal of Veterinary and Agricultural Sciences, 2023
It is impossible to imagine the epizootic well-being of poultry without immunoprophylaxis. Today, there are many vaccines to prevent infectious diseases in poultry.
T. S. Budnik, S. V. Guralska
doaj   +1 more source

Clinlabomics‐Enabled Blending Ensemble Learning for Low‐Cost Pan‐Cancer Detection and Classification Using Routine Clinical Laboratory Data

open access: yesAdvanced Intelligent Systems, EarlyView.
Researchers develop clinlabomics assisted for cancer identification, an artificial intelligence‐powered system using routine clinical lab data to detect and identify 10 cancer types. Tested on 19 199 individuals, it achieves 90.39% sensitivity and 82.41% specificity in cancer detection, with 72.57% accuracy in identifying specific cancer types ...
Bowen Zhang   +9 more
wiley   +1 more source

Multicentric B-cell lymphoma in a pygmy goat [PDF]

open access: yes, 2016
A six-year-old, male pygmy goat was referred with a sudden onset of peripheral lymphadenopathy, which initially started as enlarged inguinal lymph nodes. Clinical examination showed swollen retropharyngeal, prescapular and inguinal lymph nodes. Serologic
Chiers, Koen   +6 more
core  

Protein S Enhances the Phagocytosis of Phosphatidylserine‐Exposing Erythrocytes: Implications in Sickle Cell Disease

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT The major anticoagulant Protein S (PROS1) also contributes to the phagocytosis of apoptotic cells by bridging exposed phosphatidylserine (PtdSer) to the MerTK receptor on macrophages (efferocytosis). Whether PROS1 is involved in the splenic clearance of PtdSer‐positive senescent and altered erythrocytes such as erythrocyte ghosts (eryghosts ...
Claire Auditeau   +26 more
wiley   +1 more source

Physiological variations of serum biochemical profile in quarter horse mares at peripartum and in their neonatal foals

open access: yesBioscience Journal, 2018
The objectives of this study were to evaluate the serum biochemical profile in Quarter Horse mares in their peripartum, and neonates on their birth date, and to compare the values obtained for male and female foals, as well as values obtained for foals ...
Fernando Cristino Barbosa   +5 more
doaj   +3 more sources

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