Results 71 to 80 of about 16,806 (319)
British Journal of Clinical Pharmacology, EarlyView.Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort +8 more
wiley +1 more source
Cancer Communications, EarlyView.Abstract Radiopharmaceuticals are reshaping the landscape of cancer therapy, offering a unique theranostic advantage that is becoming increasingly central to precision medicine. By labeling the same molecular scaffold with different radionuclides, these agents enable seamless integration of diagnostic imaging and targeted therapy.
Jing Li +6 more
wiley +1 more source
The etiological structure of mass diseases with young gastro and respiratory syndrome [PDF]
, 2016 Etiology gastroenteritis and pneumonia animals studied complex, on the basis of epizootic, clinical, pathological data, bacteriological results, serology, hematology, immunobiochemical research ...
Bukhanov, V. D. +4 more
core +4 more sources
Cereal Chemistry, EarlyView.ABSTRACT Background and Objectives This study evaluated the effect of seed shape on the composition, functional, and quality properties of pea flours and protein isolates. Wrinkled‐seed (WPAs) and round‐seed (RPA) pea accessions were selected from a genome‐wide association study panel.
Cassia Galves +4 more
wiley +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract This 2‐part, randomized, placebo‐controlled, double‐blind, Phase 1 study analyzed the pharmacokinetics, safety, and biomarker profile of fezolinetant in healthy Japanese individuals. Part 1: male participants received single doses of placebo or fezolinetant 15 or 60 mg.
Akira Koibuchi +8 more
wiley +1 more source
EVOLUTION OF THE MAIN BLOOD INDICES IN TSIGAI FATTENING SHEEP [PDF]
Journal of Central European Agriculture, 2004 Research was performed on Tsigai, Merino of Cluj, and Corriedale breeds. The main blood constants: glicemy, cholesterol, total proteins, albumins, globulins, gamma globulin, creatinine, urea and iron, were determined in order to establish the feeding ...
V MIREŞAN
doaj
ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
Primary biliary cirrhosis in classmates [PDF]
, 2002 Two former classmates aged 58 with a history of more than 20 years of elevated liver function tests presented to our clinic. As they were both tested positive for antimitochondrial antibodies and liver biopsy showed distinctive bile duct lesions, they ...
Mach, Marc-Alexander von
core
Immunogenicity of recombinant Mycobacterium bovis bacille Calmette-Guèrin clones expressing T and B cell epitopes of Mycobacterium tuberculosis antigens [PDF]
, 2013 Recombinant Mycobacterium bovis bacille Calmette-Guèrin (rBCG) expressing three T cell epitopes of Mycobacterium tuberculosis (MTB) Ag85B antigen (P1, P2, P3) fused to the Mtb8.4 protein (rBCG018) or a combination of these antigens fused to B cell ...
Acosta, Armando +6 more
core +3 more sources
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source