Results 31 to 40 of about 14,639 (152)

The prognostic significance of serum gamma-glutamyltransferase levels and AST/ALT in primary hepatic carcinoma

BMC Cancer, 2019
Background Blood counting and the liver function tests, as the routine examinations, can reflect the immune and nutritional status of the body, our aim is to assess the prognostic significance of serum gamma-glutamyltransferase (GGT) levels and AST/ALT ...
Li-xiang Zhang, Yang Lv, A-Man Xu, Huan-zhong Wang   +3 more
doaj   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Stiripentol: Unpublished results from the first phase 2 clinical trial in Lennox–Gastaut syndrome conducted in the early 1990s

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to present the results of an exploratory phase 2 trial of stiripentol in Lennox–Gastaut syndrome (LGS). Methods This exploratory single‐blind, single‐arm, nonrandomized sequential‐period phase 2 study was conducted at four centers in France between January 1989 and August 1993.
Stéphane Auvin, Benjamin Serraz, Jérémie Lespinasse, Laurent Chancharme   +3 more
wiley   +1 more source

The effect of cytoflavin on functional and metabolic parameters rat liver in pancreatonecrosis

Бюллетень сибирской медицины, 2012
Problem of diagnosis and treatment of patients with necrotizing pancreatitis is an urgent. So it is interesting to study the effectiveness of a multicomponent antihypoxant and antioxidant cytoflavin to reduce violations of the detoxifying properties of ...
M. S. Sukach, V. T. Dolgikh
doaj   +1 more source

Nutritional Potential, Phytochemical Content, In Vivo Antioxidant, and Antanemic Potential of Musa paradisiaca Flower

Food Chemistry International, EarlyView.
After collecting Musa paradisiaca leaves, some were dried and others were used to produce aqueous extracts. The extracts and powders were characterized and then administered to rats made anaemic by PHZ. After 14 days of administration of the two samples, the rats were euthanized and it was observed that after 9 days of treatment, the aqueous extract ...
Josée Rebeca Nombo, Jethro Roland Misse Ngangue Ekwala, Somon Régine Tuem, Stéphano Tene Tambo, Merlin Ngafon Nchoutpouen, Valery Jean François Nsoga, Jules Christophe Koule Manz, Jordan Mekui Nwotue, Mathieu Ndomou   +8 more
wiley   +1 more source

Comportamento de componentes bioquímicos do sangue em equinos submetidos à ozonioterapia Profile of blood biochemistry components in horses treated with ozone therapy

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2009
O comportamento de constituintes bioquímicos sanguíneos (glicose, fibrinogênio, creatina fosfoquinase e gama-glutamiltransferase) foi monitorado, in vivo, em 12 equinos mestiços (seis machos e seis fêmeas), com idade entre 4 e 20 anos, submetidos à ...
M.A. Haddad, M.V. Souza, J.J. Hincapie, J.I. Ribeiro Junior, J.D. Ribeiro Filho, L.A. Benjamin   +5 more
doaj   +1 more source

ASTAXANTHIN MENGHAMBAT PERLEMAKAN HATI DAN PENINGKATAN KADAR SERUM GAMMA-GLUTAMYLTRANSFERASE PADA TIKUS WISTAR JANTAN YANG DIBERI MINYAK JELANTAH

Indonesian Journal of Clinical Nutrition Physician, 2020
Non-alcoholic fatty liver can be triggered by used cooking oil consumption due to the formation of free radicals and the accumulation of fatty acids in the body.
Astrid Amanda Pangalela, I Wayan Weta, Iin Indrayani Maker   +2 more
doaj   +1 more source

Prognostic impact of pretherapeutic gamma-glutamyltransferase on patients with nasopharyngeal carcinoma. [PDF]

PLoS ONE, 2017
BACKGROUND:Gamma-glutamyltransferase (GGT) is a membrane-bound enzyme involved in the metabolism of glutathione. Studies suggested that GGT played an important role in the tumor development, progression, invasion and drug resistance and prognosis.
Yue-Feng Wen, Xian-Zi Yang, Li-Si Zeng, Hai-Hua Peng, Wen-Jin Huang, Long-Mei Cai, Tong-Chong Zhou, Xiao-Dan Lin   +7 more
doaj   +1 more source

Gamma-glutamyltransferase fractions in human plasma and bile: characteristic and biogenesis. [PDF]

PLoS ONE, 2014
Total plasma gamma-glutamyltransferase (GGT) activity is a sensitive, non-specific marker of liver dysfunction. Four GGT fractions (b-, m-, s-, f-GGT) were described in plasma and their differential specificity in the diagnosis of liver diseases was ...
Irene Fornaciari, Vanna Fierabracci, Alessandro Corti, Hassan Aziz Elawadi, Evelina Lorenzini, Michele Emdin, Aldo Paolicchi, Maria Franzini   +7 more
doaj   +1 more source

A Lower Serum Gamma-Glutamyltransferase Level Does Not Predict a Sustained Virological Response in Patients with Chronic Hepatitis C Genotype 1

Gut and Liver, 2013
Background/AimsLow gamma-glutamyltransferase (GGT) level was shown to be an independent predictor of a sustained virological response (SVR) in chronic hepatitis C.
doaj   +1 more source