Results 81 to 90 of about 1,412,303 (334)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Exact Expressions for Kullback–Leibler Divergence for Univariate Distributions

Entropy
The Kullback–Leibler divergence (KL divergence) is a statistical measure that quantifies the difference between two probability distributions. Specifically, it assesses the amount of information that is lost when one distribution is used to approximate ...
Victor Nawa, Saralees Nadarajah
doaj   +1 more source

Some new results for the Srivastava-Luo-Raina $\mathbb{M}$-transform pertaining to the incomplete H-functions

AIMS Mathematics, 2020
The image formula of the incomplete H-functions is derived in this paper by using the Srivastava-Luo-Raina M-Transform. Also, we obtained the image formulae of some useful and important cases of incomplete H-function.
M. K. Bansal, D. Kumar, J. Singh, A. Tassaddiq, K. S. Nisar   +4 more
doaj   +1 more source

Robust and Sparse Regression via $\gamma$-divergence

, 2016
In high-dimensional data, many sparse regression methods have been proposed. However, they may not be robust against outliers. Recently, the use of density power weight has been studied for robust parameter estimation and the corresponding divergences ...
Fujisawa, Hironori, Kawashima, Takayuki
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

On gamma matrices of local zeta functions associated with homogeneous cones [PDF]

, 2021
Hideto Nakashima
openalex   +1 more source

Symmetries of WDVV equations

, 2005
We say that a function F(tau) obeys WDVV equations, if for a given invertible symmetric matrix eta^{alpha beta} and all tau \in T \subset R^n, the expressions c^{alpha}_{beta gamma}(tau) = eta^{alpha lambda} c_{lambda beta gamma}(tau) = eta^{alpha lambda}
Albert Schwarz, Barannikov, Dijkgraaf, Dubrovin, Givental, Maxim Kontsevich, van de Leur, Yujun Chen   +7 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Self-consistent equation for an interacting Bose gas

, 2003
We consider interacting Bose gas in thermal equilibrium assuming a positive and bounded pair potential $V(r)$ such that ...
A. Süto, B. Duplantier, C. Hemmer, D. Brydges, D.M. Ceperley, E. Lieb, E. Lieb, F. Cornu, F. Dalfovo, J. Ginibre, J. Lauwers, J. Lauwers, J.L. Lebowitz, Jaroslaw Piasecki, M. Fannes, P. Grüter, Ph. de Smedt, Philippe A. Martin, T.D. Lee, T.D. Lee, V. Ballenegger   +20 more
core   +1 more source