Results 81 to 90 of about 1,392,060 (284)

A completely monotonic function involving the gamma and trigamma functions

Kuwait Journal of Science, 2016
In the paper the author provides necessary and sufficient conditions on $a$ for the function\begin{equation*}\frac{1}{2}\ln(2\pi)-x+\biggl(x-\frac{1}{2}\biggr)\ln x-\ln\Gamma(x)+\frac1{12}{\psi'(x+a)}\end{equation*}and its negative to be completely ...
Feng Qi
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

On the integral equation of the boundary value problem for the essentially loaded differential heat operator

Қарағанды университетінің хабаршысы. Математика сериясы, 2016
In the article the Volterra integral equations of the second kind with the given kernel are investigated. This kind of integral equations arises in the solving of some boundary value problems for essential loaded differential heat operator in an ...
A.N. Yesbayev, G.A. Yessenbayeva
doaj  

Applications of the generalized gamma function to a fractional-order biological system. [PDF]

Heliyon, 2023
Matouk AE.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

On a (p,k)-analogue of the Gamma function and some associated Inequalities

Moroccan Journal of Pure and Applied Analysis, 2016
In this paper, we introduce a new two-parameter deformation of the classical Gamma function, which we call a (p,k)-analogue of the Gamma function. We also provide some identities generalizing those satisfied by the classical Gamma function.
Nantomah K., Prempeh E., Twum S. B.
doaj   +1 more source

Bounds for triple gamma functions and their ratios

Journal of Inequalities and Applications, 2016
In this work, in addition to the bounds for triple gamma function, bounds for the ratios of triple gamma functions are obtained. Similar bounds for the ratios of the double gamma functions are also obtained.
Sourav Das, A Swaminathan
doaj   +1 more source