Results 221 to 230 of about 21,783 (331)

Effects of 10- and 30-minute Hepatic Ischemia on Total Protein, Albumin, Globulin Fractions, and LDH of Male Albino Rates; An Experimental Study. [PDF]

open access: yesArch Acad Emerg Med
Ismayilova SG   +6 more
europepmc   +1 more source

Major Cat Allergen Fel d 4: Structure and Identification of a Cross‐Reactive IgE‐Epitope‐Containing Area

open access: yesAllergy, Volume 81, Issue 4, Page 1075-1088, April 2026.
This study reports the three‐dimensional structure of an important cat allergen, Fel d 4, that shares high homology with Equ c 1 (i.e., major horse allergen) and Can f 6 (i.e., dog allergen). The C‐terminal region of the Fel d 4 contains a major IgE‐reactive epitope.
Nikolina Todorović   +14 more
wiley   +1 more source

Pregnane X Receptor Regulates Human Endocrine System by Inducing Sex Hormone–Binding Globulin Expression

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 4, April 2026.
ABSTRACT Sex hormone–binding globulin (SHBG) is a sex hormone carrier. We aimed to characterize the role of pregnane X receptor (PXR), a major regulator of drug metabolism, in SHBG regulation. Serum SHBG was measured in four clinical trials (n = 61) and expression in in vitro experiments in human 3D hepatocyte spheroids and HepG2 cells.
Maria H. Ahonen   +5 more
wiley   +1 more source

Attempts to Achieve Targeted Covalent Inhibition of Hsp90β

open access: yesChemical Biology &Drug Design, Volume 107, Issue 4, April 2026.
Electrophilic warheads were incorporated into Hsp90β‐selective inhibitors to covalently modify Lys58, which occupies the solvent‐exposed region of the binding pocket. Although many inhibitors display nanomolar affinity towards Hsp90β over a 24‐h period, analyses to determine covalent bond formation with this residue were inconclusive.
Terin D'Amico   +3 more
wiley   +1 more source

THE PROBLEMS AND PROGNOSIS OF THE CHRONICALLY SURVIVING PATIENT AFTER RENAL HOMOTRANSPLANTATION [PDF]

open access: yes, 1966
Carey, TA   +7 more
core   +1 more source

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