Results 71 to 80 of about 13,532 (284)

INCREASE OF GLYCOSAMINOGLYCANS AND METALLOPROTEINASES 2 AND 9 IN LIVER EXTRACELLULAR MATRIX ON EARLY STAGES OF EXTRAHEPATIC CHOLESTASIS

open access: yesArquivos de Gastroenterologia, 2014
Context Cholestasis produces hepatocellular injury, leukocyte infiltration, ductular cells proliferation and fibrosis of liver parenchyma by extracellular matrix replacement.
Pedro Luiz Rodrigues GUEDES   +3 more
doaj   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

The Effect of Cinnamon Extract on Serum Proteins Levels of Male Balb/c Mice

open access: yesArmaghane Danesh Bimonthly Journal, 2011
Background & Aim: Cinnamon is a plant with many pharmaceutical effects. The present research evaluated the effects of Cinnamon bark extract on serum proteins level in male Balb/c mice.
M Modaresi
doaj  

Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome [PDF]

open access: yesOpen Veterinary Journal, 2015
A 12 year old, 38 kg, mix-breed, intact male dog presented with a 20 day history of clinical signs consistent with hyperviscosity syndrome secondary to multiple myeloma.
I. Lippi   +5 more
doaj  

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper   +6 more
wiley   +1 more source

Morphometric and haematological parameters in Italian Mediterranean Buffaloes finished with different diets

open access: yesItalian Journal of Animal Science, 2010
Twenty four weaned male buffalo calves where randomly divided in two groups: group 1 fed unifeed of corn silage, hay, maize meal and soybean meal until slaughter, and group 2 fed the same diet until they reached 325 kg of body weight, then fed alfalfa ...
A. Borghese   +5 more
doaj   +1 more source

Integrated Use of Oxidative Stress and Histological Biomarkers of T. tinca as Indicators of 17‐Alpha‐Ethynylestradiol Exposure

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The potential adverse effects of 17‐alpha‐ethynylestradiol (50, 100, and 500 μg EE2/kg b.w., for 30 days) on tench (Tinca tinca) were evaluated by integrating biomarkers including physiological (hepato‐somatic index, spleen‐somatic index, and hematocrit), oxidative stress (catalase, glutathione peroxidase, and glutathione reductase activities;
Ana L. Oropesa   +3 more
wiley   +1 more source

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