Results 121 to 130 of about 15,435 (232)

SLC7A5 promotes colorectal cancer liver metastasis by reprogramming tryptophan metabolism through the Kyn/XANA‒AhR axis and reshaping the immune microenvironment

open access: yesClinical and Translational Medicine, Volume 16, Issue 8, August 2026.
SLC7A5‒Kyn/XANA signalling activates AhR to drive EMT and metastatsis. SLC7A5 knockdown enhances macrophage antigen presentation and reverses CD8+ T‐cell exhaustion. SLC7A5 knockdown induces antigen‐driven and IgG‐secreting B‐cell clonal expansion. Combination of SLC7A5 inhibition and anti‐PD‐1 therapy offers clinical targeting.
Yaohao Luo   +8 more
wiley   +1 more source

Integrated Evaluation of the Multifunctional Bioactivity of Curcuma zedoaria (Christm.) Roscoe Essential Oil: Antimicrobial, Insecticidal, and Postharvest Effects on Fresh Ginger

open access: yeseFood, Volume 7, Issue 4, August 2026.
Multifunctional bioactivity of Curcuma zedoaria essential oil. ABSTRACT Plant‐derived essential oils are increasingly investigated as sustainable alternatives for food preservation and crop protection; however, their multifunctional applicability under postharvest conditions remains insufficiently explored.
Miroslava Kačániová   +9 more
wiley   +1 more source

Real‐world‐data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy

open access: yesEpilepsia Open, Volume 11, Issue 4, Page 1184-1199, August 2026.
Abstract Objectives The objectives of this study were to develop a real‐world‐data (RWD) database for patients with epilepsy to provide further real‐world‐evidence (RWE) for monogenic genetic epilepsies; to assess the usefulness of a diagnostic algorithm in epilepsy; and to examine protein 3D structures using in silico tools to predict variant ...
Haley Morris   +4 more
wiley   +1 more source

Gamma Knife Stereotactic Radiosurgery With a Reduced Peripheral Dose: Outcomes in Uveal Melanoma Patients. [PDF]

open access: yesAdv Radiat Oncol
Kollitz L   +13 more
europepmc   +1 more source

Inhibiting the Endothelial Mechanosensitive Channel Piezo1 Restores Hippocampal Blood–Brain Barrier Integrity to Improve Anesthesia‐ and Surgery‐Induced Cognitive Decline

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Approximately 10%–30% of elderly patients develop cognitive decline after surgery. How brain regions coordinate cellular networks to mediate this remains unclear. Anesthesia/surgery induces Piezo1 in hippocampal endothelial cells of aged mice. Endothelial Piezo1 deletion restores BBB integrity and improves cognition.
Yong Qiu   +13 more
wiley   +1 more source

An advanced automated pipeline for brain tumour segmentation on magnetic resonance imaging for gamma knife radiosurgery. [PDF]

open access: yesPhys Imaging Radiat Oncol
Ramachandran P   +11 more
europepmc   +1 more source

Long‐Term Local Control and Mortality After Transpupillary Thermotherapy of Small Uveal Melanomas

open access: yesClinical &Experimental Ophthalmology, Volume 54, Issue 6, Page 832-844, August 2026.
ABSTRACT Background Transpupillary thermotherapy (TTT) is used for selected small choroidal melanocytic tumours, either as primary treatment or as an adjunct to plaque brachytherapy. We compared long‐term local recurrence and mortality outcomes after primary TTT alone, plaque brachytherapy combined with TTT (brachy+TTT), and plaque brachytherapy alone (
Maria Fili   +5 more
wiley   +1 more source

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