Results 71 to 80 of about 1,029,566 (295)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Method of almost convergence with operator of the form fractional order and applications

, 2016
The purpose of this paper is twofold. First, basic concepts such as Gamma function, almost convergence, fractional order difference operator and sequence spaces are given as a survey character.
Kadak, Ugur, Kirisci, Murat
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

A new analysis of 14O beta decay: branching ratios and CVC consistency

, 2005
The ground-state Gamow-Teller transition in the decay of 14O is strongly hindered and the electron spectrum deviates markedly from the allowed shape. A reanalysis of the only available data on this spectrum changes the branching ratio assigned to this ...
B. H. Wildenthal, H. Behrens, H. Behrens, I. S. Towner, J. C. Hardy   +4 more
core   +1 more source

The impact of sterilization upon extracellular matrix hydrogel structure and function

Journal of Immunology and Regenerative Medicine, 2018
Extracellular matrix (ECM) hydrogels represent a growing subset of injectable biomaterials for tissue engineering and regenerative medicine applications.
L. White, Timothy J. Keane, Adam Smoulder, Li Zhang, Arthur A. Castleton, J. Reing, N. Turner, C. Dearth, S. Badylak   +8 more
semanticscholar   +1 more source

A comparative study between nano-cadmium oxide and lead oxide reinforced in high density polyethylene as gamma rays shielding composites

, 2020
In this work, polymer composites of high density polyethylene reinforced by micro-sized and nanosized cadmium oxide, lead oxide, and a mixture of both with filler weight fraction of 30% were prepared by compression molding technique and characterized ...
A. G. Alharshan, A. Aloraini, M. Abd, S. Badawi, T. M. Alabsy, I. Abbas, M. El-Khatib   +6 more
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

On a Generalized Difference Sequence Spaces of Fractional Order associated with Multiplier Sequence Defined by A Modulus Function

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2020
Let Γ(m) denotes the gamma function of a real number m∉{0,-1,-2,…}. Then the difference matrix Δ^α of a fractional order α is defined as (Δ^α v)_k=∑_i〖(-1)^i (Γ(α+1))/(i!Γ(α-i+1)) v_(k+i) 〗.Using the difference operator Δ^α, we introduce paranormed ...
Taja Yayıng
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Classical special functions of matrix arguments

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï
This article focuses on a few of the most commonly used special functions and their key properties and defines an analytical approach to building their matrix-variate counterparts.
Dmytro Shutiak, Gleb Podkolzin, Victor Bondarenko, Yury Chapovsky   +3 more
doaj   +1 more source