Results 161 to 170 of about 36,242 (250)

Functional characterization of 42 CK2α de novo variants associated with Okur‐Chung neurodevelopmental syndrome

The FEBS Journal, EarlyView.
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast, Christian Werner, Karsten Niefind, Joachim Jose   +3 more
wiley   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

Study on the EEG Rhythm in Meditation

, 2014
Meditation affects the brain rhythm significantly. Compared with 4 non-meditators, the power of delta band was lower while high frequency band was 5 higher for a meditator.
Liljenström, Hans,, Sveriges lantbruksuniversitet.   +1 more
core  

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

The FEBS Journal, EarlyView.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril, Matthieu Le Gallo, Elodie Lafont   +2 more
wiley   +1 more source

Network dynamics contribute to a gamma rhythm highly robust to synaptic variation [PDF]

BMC Neurosci, 2014
Hauser S, Reimers M.
europepmc   +1 more source

From Sprinters to Marathoners: Rethinking Therapeutic Speed and Disease Modification in Atopic Dermatitis

Allergy, EarlyView.
Thomas Bieber, Felix Lauffer
wiley   +1 more source

Deficient inhibition of irrelevant visual information in migraine: A magnetoencephalography study of alpha‐band activity

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background There is growing evidence that migraine is associated with attentional abnormalities, both during and between attacks, potentially affecting the cognitive processing of sensory stimulation. However, the underlying neurophysiological mechanism remains poorly understood.
Rémy Masson, Alma ElShafei, Geneviève Demarquay, Lesly Fornoni, Yohana Lévêque, Anne Caclin, Aurélie Bidet‐Caulet   +6 more
wiley   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

Journal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams, Les N. Harris, Jean‐Sébastien Moore, Ella K. Middleton, Shira A. Berkelhammer, Ben Speers‐Roesch, Matthew J. H. Gilbert   +6 more
wiley   +1 more source

Gamma rhythm low field magnetic stimulation alleviates neuropathologic changes and rescues memory and cognitive impairments in a mouse model of Alzheimer's disease. [PDF]

Alzheimers Dement (N Y), 2017
Zhen J, Qian Y, Weng X, Su W, Zhang J, Cai L, Dong L, An H, Su R, Wang J, Zheng Y, Wang X.   +11 more
europepmc   +1 more source

Gamma low field magnetic stimulation ameliorates pathophysiological damage and cognitive impairments in AD mice. [PDF]

Alzheimers Res Ther
Zheng W, Geng D, Wang A, Li Z, Liu A, Chen S, Wang Q, Su C, Yan Z, Yin Y, Xu G.   +10 more
europepmc   +1 more source