Results 171 to 180 of about 25,969 (247)

AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling. [PDF]

Cell Death Dis, 2022
Ferrarotto R, Mishra V, Herz E, Yaacov A, Solomon O, Rauch R, Mondshine A, Motin M, Leibovich-Rivkin T, Davis M, Kaye J, Weber CR, Shen L, Pearson AT, Rosenberg AJ, Chen X, Singh A, Aster JC, Agrawal N, Izumchenko E.   +19 more
europepmc   +1 more source

Gamma-Secretase Subunit PEN-2 [PDF]

, 2020
openaire   +1 more source

Effects of a gamma-secretase inhibitor of notch signalling on transforming growth factor β1-induced urethral fibrosis. [PDF]

J Cell Mol Med, 2021
Huang S, Fu D, Wan Z, Li M, Li H, Chong T.   +5 more
europepmc   +1 more source

Gamma secretase inhibitors, DAPT and MK0752, exhibit synergistic anticancer effects with cisplatin and docetaxel in 2D and 3D models of breast cancer. [PDF]

Turk J Biol
Telli K, Gubat J, D'Arcy P, Yalçin Özuysal Ö.   +3 more
europepmc   +1 more source

New onset hidradenitis suppurativa and eruptive milia associated with gamma secretase inhibitor therapy in a patient with desmoid tumor: A case report. [PDF]

JAAD Case Rep
Gutierrez Y, DeClerck B, Hsiao JL, Lee KH.   +3 more
europepmc   +1 more source

Air pollution amyloidogenesis is attenuated by the gamma-secretase modulator GSM-15606. [PDF]

Alzheimers Dement
Godoy-Lugo JA, Thorwald MA, Cacciottolo M, D'Agostino C, Chakhoyan A, Sioutas C, Tanzi RE, Rynearson KD, Finch CE.   +8 more
europepmc   +1 more source

DR-5 and DLL-4 mAb Functionalized SLNs of Gamma-Secretase Inhibitors- An Approach for TNBC Treatment. [PDF]

Adv Pharm Bull, 2021
Kumari M, Krishnamurthy PT, Pinduprolu SKSS, Sola P.   +3 more
europepmc   +1 more source

A novel generation of potent gamma-secretase modulators: Combat Alzheimer's disease and Down syndrome-associated Alzheimer's disease. [PDF]

Neural Regen Res
Chen XQ.
europepmc   +1 more source

Allogeneic Anti-BCMA CAR T Cells Are Superior to Multiple Myeloma-derived CAR T Cells in Preclinical Studies and May Be Combined with Gamma Secretase Inhibitors. [PDF]

Cancer Res Commun, 2022
Metelo AM, Jozwik A, Luong LA, Dominey-Foy D, Graham C, Attwood C, Inam S, Dunlop A, Sanchez K, Cuthill K, Rice C, Streetly M, Bentley T, Boldajipour B, Sommer C, Sasu B, Benjamin R.   +16 more
europepmc   +1 more source

Presenilin/gamma-secretase regulates neurexin processing at synapses

, 2011
This work was supported by grants from the Junta de Andalucía, Consejería de Innovación, Ciencia y Empresa to FGS (Proyecto de Excelencia P07-CVI-02943) and Ministerio de Ciencia e Innovación of Spain to CAS (SAF2010-20925 and CIBERNED CB06/05/0042).
Gómez Scholl, Francisco Manuel, Servián Morilla, Emilia, Saura, Carlos A.   +2 more
openaire   +2 more sources