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Pulsed Ultrahigh Frequency Spinal Cord Stimulation for Arrhythmia After Myocardial Infarction [PDF]

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Acute myocardial infarction (MI) increases sympathetic tone and increases the risk of life‐threatening ventricular arrhythmias. We tested the hypothesis that spinal cord stimulation (SCS) using pulsed ultrahigh frequency (PUF) from T1 to T3 ...
Chin‐Yu Lin   +12 more
doaj   +2 more sources

Decreased Myocardial 123I‐MIBG Uptake Without Sympathetic Denervation: An Autopsy Report of Autoimmune Autonomic Ganglionopathy [PDF]

open access: yesBrain and Behavior
Introduction Autoimmune autonomic ganglionopathy (AAG) is a rare disorder characterized by widespread autonomic failure due to antibodies targeting the ganglionic nicotinic acetylcholine receptor (gAChR).
Daisuke Taniguchi   +7 more
doaj   +2 more sources

Protocol of the RADIO-STAR trial: a phase 1 safety and dose finding study of hypofractionated radiotherapy to the stellate ganglia for the treatment of ventricular arrhythmia [PDF]

open access: yesBMJ Open
Introduction Sympathetic activation is the hallmark of cardiac disease, driving disease progression and triggering ventricular arrhythmia (VA). Despite optimal medical therapy, many patients experience recurrent VAs refractory to medical therapy, leading
Fintan Sheerin   +11 more
doaj   +2 more sources

Tyrosine Hydroxylase-Expressing Neurons in the Vagal Ganglia: Characterization and Implications [PDF]

open access: yesBiomedicines
Background/Objectives: A combination of sympathoexcitation and parasympathetic withdrawal contributes to the occurrence of ventricular arrhythmias, sudden cardiac death, and progression of heart failure after myocardial injury.
Artin Khaky   +5 more
doaj   +2 more sources

Neurocardiac Crosstalk: Sympathetic Remodeling and Arrhythmogenesis After Myocardial Infarction [PDF]

open access: yesCurrent Issues in Molecular Biology
Sympathetic remodeling following myocardial infarction (MI) is a critical mechanism underlying the development of malignant arrhythmias and sudden cardiac death (SCD).
Tianshui Yu
doaj   +2 more sources

Post-Ganglionic Sympathetic Neurons can Directly Sense Raised Extracellular Na+ via SCN7a/Nax

open access: yesFrontiers in Physiology, 2022
The relationship between dietary NaCl intake and high blood pressure is well-established, and occurs primarily through activation of the sympathetic nervous system.
Harvey Davis   +5 more
doaj   +1 more source

Untangling Peripheral Sympathetic Neurocircuits

open access: yesFrontiers in Cardiovascular Medicine, 2022
The sympathetic nervous system plays a critical role in regulating many autonomic functions, including cardiac rhythm. The postganglionic neurons in the sympathetic chain ganglia are essential components that relay sympathetic signals to target tissues ...
Courtney Clyburn   +3 more
doaj   +1 more source

The role of the Notch signalling pathway in regulating the balance between neuronal and nonneuronal cells in sympathetic ganglia and the adrenal gland.

open access: yesPLoS ONE, 2023
Sympathetic neurons and endocrine chromaffin cells of the adrenal medulla are catecholaminergic cells that derive from the neural crest. According to the classic model, they develop from a common sympathoadrenal (SA) progenitor that has the ability to ...
Stella Shtukmaster, Katrin Huber
doaj   +2 more sources

Satellite glial cells modulate cholinergic transmission between sympathetic neurons.

open access: yesPLoS ONE, 2020
Postganglionic sympathetic neurons and satellite glial cells are the two major cell types of the peripheral sympathetic ganglia. Sympathetic neurons project to and provide neural control of peripheral organs and have been implicated in human disorders ...
Joana Enes   +6 more
doaj   +1 more source

Isolation and Electrophysiology of Murine Sympathetic Postganglionic Neurons in the Thoracic Paravertebral Ganglia

open access: yesBio-Protocol, 2021
The thoracic paravertebral sympathetic chain postganglionic neurons (tSPNs) represent the predominant sympathetic control of vascular function in the trunk and upper extremities.
Mallika Halder   +4 more
doaj   +1 more source

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